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CTBS Knockout Cell Lines

Gene: CTBS

Official Full Name: chitobiaseprovided by HGNC

Gene Summary: Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38363 CTBS Knockout cell line (HeLa) Human CTBS 1:3~1:6 Negative Online Inquiry
KO38364 CTBS Knockout cell line (HCT 116) Human CTBS 1:2~1:4 Negative Online Inquiry
KO38365 CTBS Knockout cell line (A549) Human CTBS 1:3~1:4 Negative Online Inquiry

Background

CTBS Gene Knockout Cell Lines represent a pivotal advancement in the field of genetic research, designed to facilitate the study of gene function and the impact of gene disruption on cellular processes. These cell lines are generated through sophisticated gene-editing techniques, most prominently CRISPR/Cas9, allowing for precise knockout of the CTBS (chondroitin sulfate N-acetylgalactosaminyltransferase) gene. By eliminating the expression of CTBS, researchers can investigate its role in various biological pathways, providing insights into developmental processes and disease mechanisms, particularly in conditions such as cancer and neurological disorders.

The primary mechanism behind these knockout cell lines involves the use of engineered nucleases that create double-strand breaks in the genome, leading to insertions or deletions during the DNA repair process. This targeted disruption allows researchers to observe the resultant phenotypic changes and biochemical pathways that are affected by the absence of the CTBS gene, thereby contributing to a deeper understanding of gene functionality in a cellular context.

The scientific utility of CTBS Gene Knockout Cell Lines is extensive, offering applications in both fundamental and applied research. In clinical settings, these cell lines can serve as valuable tools for drug screening, biomarker discovery, and the development of new therapeutic strategies by providing models that closely mimic human disease states.

What sets CTBS Gene Knockout Cell Lines apart from traditional cell lines or alternative genetic manipulation methods is their rigorous validation and specificity. These cell lines undergo extensive characterization to ensure reliable gene disruption and reproducibility of results, which is critical for producing scientifically valid data. Moreover, their ability to mimic human physiological conditions makes them ideal for translational research, giving researchers a unique edge in their investigations.

In summary, the value of CTBS Gene Knockout Cell Lines lies in their ability to significantly advance genetic research and therapeutic development through precise gene editing. Our company prides itself on providing high-quality biological products, supported by a team of experts who ensure that our offerings meet the highest scientific standards, thereby empowering researchers and clinicians to unlock new discoveries and innovations in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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