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CST1 Knockout Cell Lines

Gene: CST1

Official Full Name: cystatin SNprovided by HGNC

Gene Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38385 CST1 Knockout cell line (HCT 116) Human CST1 1:2~1:4 Negative Online Inquiry
KO38386 CST1 Knockout cell line (A549) Human CST1 1:3~1:4 Negative Online Inquiry

Background

CST1 Gene Knockout Cell Lines are essential research tools that enable scientists to study the functional roles of the CST1 gene in a controlled cellular environment. These cell lines are specifically engineered to have the CST1 gene inactivated or “knocked out,” allowing for the investigation of gene function and the phenotypic consequences of its absence. By utilizing CRISPR-Cas9 and other state-of-the-art genome-editing techniques, these knockout cell lines provide a precise and reliable model to elucidate the biological pathways associated with CST1.

The mechanism of action for CST1 gene knockout involves the targeted disruption of the genomic sequence encoding the CST1 gene, leading to the cessation of its protein expression. This allows researchers to assess the downstream effects on cellular processes such as immune response modulation, inflammation, and cellular communication. The implications of knocking out CST1 are vast, opening avenues for studies in various conditions where this gene plays a crucial role, particularly in cancer research and the investigation of fibrotic diseases.

From a scientific standpoint, CST1 Gene Knockout Cell Lines hold significant importance in both fundamental and translational research. They allow for a targeted approach in dissecting complex biological systems, enabling researchers to delineate the role of CST1 in cellular homeostasis and disease mechanisms. Compared to traditional cell lines, CST1 knockout models offer greater specificity and relevance for gene function studies, translating to more accurate experimental outcomes.

The advantages of choosing CST1 Gene Knockout Cell Lines over alternative models include their enhanced validity and reproducibility in experiments, alongside the comprehensive data we provide pertaining to characterization and validation. This positions our product as a valuable asset for laboratories focused on cutting-edge research and therapeutic development.

Offering these optimized cell lines stems from our company’s extensive expertise in genetic engineering and cellular biology. We are committed to supporting the scientific community by providing high-quality biological products that empower researchers and clinicians to unlock new discoveries in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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