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CSNK1G3 Knockout Cell Lines

Gene: CSNK1G3

Official Full Name: casein kinase 1 gamma 3provided by HGNC

Gene Summary: This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10084 CSNK1G3 Knockout cell line (HeLa) Human CSNK1G3 1:3~1:6 Negative Online Inquiry
KO10085 CSNK1G3 Knockout cell line (HCT 116) Human CSNK1G3 1:2~1:4 Negative Online Inquiry
KO10086 CSNK1G3 Knockout cell line (HEK293) Human CSNK1G3 1:3~1:6 Negative Online Inquiry
KO10087 CSNK1G3 Knockout cell line (A549) Human CSNK1G3 1:3~1:4 Negative Online Inquiry

Background

CSNK1G3 Gene Knockout Cell Lines are specially developed cellular models designed for the functional analysis of the casein kinase 1 gamma 3 (CSNK1G3) gene. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines have been engineered to lack functional CSNK1G3 proteins, allowing researchers to investigate the biological consequences of gene loss in various cellular contexts. This product provides a robust platform for studying the role of CSNK1G3 in cellular signaling, development, and disease.

The primary mechanism through which CSNK1G3 Gene Knockout Cell Lines operate involves the disruption of critical phosphorylation pathways that are mediated by the CSNK1G3 protein. CSNK1G3 is implicated in various cellular processes including circadian rhythm regulation, Wnt signaling, and cell cycle control. By observing the cellular behaviors and phenotypic alterations in these knockout lines, researchers can elucidate the roles and downstream effects of CSNK1G3, thus contributing valuable insights into developmental biology and potential therapeutic targets.

The scientific significance of CSNK1G3 Gene Knockout Cell Lines lies in their application across multiple research domains, including cancer research and neurobiology. With an increasing body of evidence linking CSNK1G3 to various pathologies, understanding its function can accelerate the discovery of novel biomarkers and treatment strategies.

Compared to conventional models or other gene-editing technologies, CSNK1G3 Gene Knockout Cell Lines offer unmatched precision and reliability. Our cell lines are rigorously validated to ensure a complete knockout, providing high reproducibility in experimental results. Furthermore, these cell lines are available in various genetic backgrounds, catering to the specific needs of diverse research applications.

For researchers and clinicians seeking to unravel the complexities of gene function, CSNK1G3 Gene Knockout Cell Lines represent a vital resource. Their ability to mimic human disease states makes them indispensable for both translational and basic research. With a legacy of innovation and excellence, our company is committed to advancing scientific discovery by providing high-quality biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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