Gene: CSNK1G2
Official Full Name: casein kinase 1 gamma 2provided by HGNC
Gene Summary: Enables protein serine/threonine kinase activity. Predicted to be involved in endocytosis; positive regulation of canonical Wnt signaling pathway; and signal transduction. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10088 | CSNK1G2 Knockout cell line (HeLa) | Human | CSNK1G2 | 1:3~1:6 | Negative | Online Inquiry |
KO10089 | CSNK1G2 Knockout cell line (HCT 116) | Human | CSNK1G2 | 1:2~1:4 | Negative | Online Inquiry |
KO10090 | CSNK1G2 Knockout cell line (HEK293) | Human | CSNK1G2 | 1:3~1:6 | Negative | Online Inquiry |
KO10091 | CSNK1G2 Knockout cell line (A549) | Human | CSNK1G2 | 1:3~1:4 | Negative | Online Inquiry |
CSNK1G2 Gene Knockout Cell Lines are specifically engineered cellular models in which the CSNK1G2 gene has been inactivated, allowing researchers to study its functional role in various biological processes. Through the use of precise CRISPR-Cas9 gene editing technology, these cell lines enable the detailed investigation of the cellular mechanisms governed by the CSNK1G2 gene, which encodes a member of the casein kinase family involved in numerous signal transduction pathways.
The primary mechanism of the CSNK1G2 gene involves the regulation of cellular processes such as circadian rhythms, Wnt signaling, and cell proliferation. By systematically knocking out this gene, researchers can observe phenotypic changes, biochemical alterations, and downstream signaling effects, thereby enhancing our understanding of its roles in cellular physiology and pathology.
The scientific importance of these cell lines lies in their potential applications in both research and clinical settings. For instance, studies utilizing CSNK1G2 knockout models can advance our knowledge of neurodegenerative diseases, cancer, and metabolic disorders where aberrant signaling pathways are implicated. They can serve as invaluable tools for drug discovery, allowing scientists to test therapeutic compounds in a relevant biological context.
Unique selling points of our CSNK1G2 knockout cell lines include their high specificity, reproducibility, and the comprehensive characterization data we provide, which ensures accurate and reliable experimental outcomes. Compared to traditional methods, these cell lines facilitate faster experimental designs while minimizing off-target effects, ultimately enhancing research efficiency.
The value of CSNK1G2 Gene Knockout Cell Lines to researchers and clinicians is multi-faceted. They not only accelerate the discovery of novel therapies but also aid in the elucidation of complex biological phenomena, making significant contributions to the field of molecular biology and genetics.
Our company specializes in advanced genetic tools and innovations, offering a diverse portfolio of high-quality cell lines and genetic products tailored to meet the needs of the scientific community. With a commitment to excellence and a focus on pioneering research, we empower researchers to push the boundaries of knowledge and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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