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CRELD2 Knockout Cell Lines

Gene: CRELD2

Official Full Name: cysteine rich with EGF like domains 2provided by HGNC

Gene Summary: Predicted to enable calcium ion binding activity and protein disulfide isomerase activity. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular space. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09413 CRELD2 Knockout cell line (HeLa) Human CRELD2 1:3~1:6 Negative Online Inquiry
KO09414 CRELD2 Knockout cell line (HCT 116) Human CRELD2 1:2~1:4 Negative Online Inquiry
KO09415 CRELD2 Knockout cell line (HEK293) Human CRELD2 1:3~1:6 Negative Online Inquiry
KO09416 CRELD2 Knockout cell line (A549) Human CRELD2 1:3~1:4 Negative Online Inquiry

Background

CRELD2 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate in-depth investigations into the function of the CRELD2 gene, known for its association with various biological processes and pathologies. These cell lines have been developed using advanced CRISPR-Cas9 technology, which allows for precise gene editing by introducing targeted mutations that completely inactivate the CRELD2 gene. The knockout of this gene provides a robust platform to study alterations in cellular behavior and signaling pathways, making it an invaluable tool in both basic and applied biological research.

The primary function of the CRELD2 Gene Knockout Cell Lines is to elucidate the role of CRELD2 in cellular processes such as development, differentiation, and response to stress. By observing the phenotype of cells lacking CRELD2, researchers can uncover its impact on various signaling cascades, potentially leading to breakthroughs in understanding diseases such as congenital heart defects, where CRELD2 has been implicated. These knockout models can serve as critical intermediates in drug discovery, enabling scientists to screen for therapeutic candidates that either rectify the pathological consequences of CRELD2 deficiency or target associated pathways.

Compared to alternatives such as overexpression systems or knockdown methodologies, CRELD2 Gene Knockout Cell Lines offer the advantage of more complete functional ablation of the gene, thereby providing clearer insights into its biological significance. The null-effect observed in these lines allows for a more accurate interpretation of cellular phenomena, making them particularly useful for dissecting complex genetic interactions.

For researchers and clinicians, the value of the CRELD2 Gene Knockout Cell Lines cannot be overstated. They empower scientific inquiry into gene-function relationships with unprecedented clarity, paving the way for innovative approaches in both regenerative medicine and genetic disorder studies. In clinical settings, understanding the precise role of CRELD2 could lead to novel diagnostic and therapeutic options.

Our company is at the forefront of providing high-quality biological products, leveraging decades of research expertise and cutting-edge technology to support the scientific community in unraveling the complexities of gene function and fostering advances that can lead to transformative health solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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