Gene: CRELD1
Official Full Name: cysteine rich with EGF like domains 1provided by HGNC
Gene Summary: This gene encodes a member of a subfamily of epidermal growth factor-related proteins. The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18530 | CRELD1 Knockout cell line (HeLa) | Human | CRELD1 | 1:3~1:6 | Negative | Online Inquiry |
KO18531 | CRELD1 Knockout cell line (HCT 116) | Human | CRELD1 | 1:2~1:4 | Negative | Online Inquiry |
KO18532 | CRELD1 Knockout cell line (HEK293) | Human | CRELD1 | 1:3~1:6 | Negative | Online Inquiry |
KO18533 | CRELD1 Knockout cell line (A549) | Human | CRELD1 | 1:3~1:4 | Negative | Online Inquiry |
CRELD1 Gene Knockout Cell Lines are advanced in vitro models designed to facilitate the evaluation of CRELD1 gene function and the investigation of related pathophysiological processes. These genetically engineered cell lines are created by precise gene editing techniques, such as CRISPR/Cas9, that disrupt the CRELD1 gene, allowing researchers to study the resulting phenotypic alterations.
The knockout of CRELD1 leads to the disruption of the protein's role in cellular processes, including developmental signaling and cell adhesion. This product empowers researchers to dissect the mechanisms underlying diseases where CRELD1 is implicated, such as congenital heart defects and other genetic disorders. By comparing the knockout lines with wild-type controls, scientists can analyze the downstream effects on cellular behavior, gene expression, and overall cellular pathology.
The scientific importance of CRELD1 Gene Knockout Cell Lines transcends basic research; they hold promising applications in drug discovery, genetic screening, and therapeutic interventions. By providing a platform for targeted investigations, these cell lines enable the identification of potential drug targets and facilitate the evaluation of therapeutic strategies for diseases associated with CRELD1 dysregulation.
One of the standout advantages of our CRELD1 Gene Knockout Cell Lines is their high specificity and reproducibility, ensuring that results are reliable and scientifically valid. Unlike broader gene expression inhibition methods, these knockout lines offer a clear and defined genetic background, which is essential for unambiguous data interpretation. In addition, our cell lines are meticulously validated for stability and functionality, allowing researchers to have confidence in the results obtained.
For researchers and clinicians keen to unravel the complexities of CRELD1-related biology, this product represents an invaluable tool that accelerates discovery and innovation. Our commitment to excellence in biological products, coupled with our expertise in gene editing technologies, positions us as a trusted partner in advancing scientific understanding and improving therapeutic outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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