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CREBRF Knockout Cell Lines

Gene: CREBRF

Official Full Name: CREB3 regulatory factorprovided by HGNC

Gene Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of endoplasmic reticulum unfolded protein response; positive regulation of protein catabolic process; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01900 CREBRF Knockout cell line (HeLa) Human CREBRF 1:3~1:6 Negative Online Inquiry
KO01901 CREBRF Knockout cell line (HCT 116) Human CREBRF 1:2~1:4 Negative Online Inquiry
KO01902 CREBRF Knockout cell line (HEK293) Human CREBRF 1:3~1:6 Negative Online Inquiry
KO01903 CREBRF Knockout cell line (A549) Human CREBRF 1:3~1:4 Negative Online Inquiry

Background

CREBRF Gene Knockout Cell Lines are a sophisticated tool designed for researchers seeking to explore the functional dynamics of the CREBRF gene within various biological contexts. These cell lines have been specifically engineered using CRISPR-Cas9 technology to induce precise gene deletions, allowing for the comprehensive study of CREBRF's role in cellular processes such as metabolism, growth regulation, and stress responses.

The primary function of these knockout cell lines lies in their ability to elucidate the impact of CREBRF gene disruption on cellular pathways and phenotypic outcomes. By observing changes in protein expression, signaling pathways, and cellular behavior, researchers gain invaluable insights into the gene's involvement in health and disease. Furthermore, these cell lines are crucial for drug discovery and development, as they enable the identification of potential therapeutic targets and methodologies for intervention.

The scientific importance of CREBRF gene knockout cell lines is underscored by their applications in both basic biological research and clinical settings, particularly in understanding metabolic disorders, obesity, and related health issues. Such models facilitate hypothesis testing and provide a controlled environment for researchers to examine the consequences of gene loss on cellular function and viability.

Unique to our offerings, these knockout cell lines are rigorously validated for specificity and consistency, surpassing competitors in quality and reliability. The precision of our gene editing ensures that researchers can depend on robust data to inform their inquiries, ultimately leading to more effective findings and outcomes.

For researchers and clinicians alike, the value of CREBRF Gene Knockout Cell Lines lies in their ability to provide clarity in gene function studies, guiding innovation and potential therapeutic strategies. With our background in cutting-edge genetic technologies and commitment to product excellence, we position ourselves as a trusted partner in advancing biological research and clinical application.

Please note that all services are for research use only. Not intended for any clinical use.

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