Gene: CREB3L4
Official Full Name: cAMP responsive element binding protein 3 like 4provided by HGNC
Gene Summary: This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10384 | CREB3L4 Knockout cell line (HeLa) | Human | CREB3L4 | 1:3~1:6 | Negative | Online Inquiry |
KO10385 | CREB3L4 Knockout cell line (HCT 116) | Human | CREB3L4 | 1:2~1:4 | Negative | Online Inquiry |
KO10386 | CREB3L4 Knockout cell line (HEK293) | Human | CREB3L4 | 1:3~1:6 | Negative | Online Inquiry |
KO10387 | CREB3L4 Knockout cell line (A549) | Human | CREB3L4 | 1:3~1:4 | Negative | Online Inquiry |
CREB3L4 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the CREB3L4 gene, a member of the CREB/ATF family of transcription factors. This vital product provides researchers with a unique tool to study the precise biological functions of CREB3L4 in various cellular processes, including stress response, cellular differentiation, and apoptosis. By utilizing CRISPR/Cas9 technology for the generation of these knockout lines, researchers can achieve a targeted and permanent disruption of the CREB3L4 gene, enabling them to investigate the consequential effects on gene expression and metabolic pathways.
The key function of these knockout cell lines lies in their ability to unveil the role of CREB3L4 within signal transduction processes. By observing the phenotypic and functional changes in the absence of this gene, scientists can explore its implications in diseases such as cancer and metabolic disorders, providing invaluable insights into therapeutic targets and drug development. In clinical settings, understanding CREB3L4 can correlate with patient outcomes, making these cell lines pivotal for translational research.
Compared to traditional knockdown methods, such as RNA interference, CREB3L4 Gene Knockout Cell Lines offer enhanced specificity and durability, eliminating transient effects and ensuring robust experimental reproducibility. They serve as a more reliable platform for drug screening and functional assays, giving researchers confidence in their findings. Moreover, the absence of off-target effects typically associated with transient approaches enhances the reliability of experimental results.
For researchers and clinicians aiming to delve deeper into the molecular mechanisms underlying various diseases, these knockout cell lines provide an unparalleled opportunity. With our company's extensive expertise in the synthesis and validation of knockout cell lines, we ensure the highest level of quality and reliability in our products. By choosing CREB3L4 Gene Knockout Cell Lines, users are assured of a potent tool for advancing their research and clinical applications, paving the way for future discoveries in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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