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CPNE1 Knockout Cell Lines

Gene: CPNE1

Official Full Name: copine 1provided by HGNC

Gene Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02304 CPNE1 Knockout cell line (HeLa) Human CPNE1 1:3~1:6 Negative Online Inquiry
KO02305 CPNE1 Knockout cell line (HCT 116) Human CPNE1 1:2~1:4 Negative Online Inquiry
KO02306 CPNE1 Knockout cell line (HEK293) Human CPNE1 1:3~1:6 Negative Online Inquiry
KO02307 CPNE1 Knockout cell line (A549) Human CPNE1 1:3~1:4 Negative Online Inquiry

Background

CPNE1 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to disrupt the expression of the copine-1 gene (CPNE1). This product enables researchers to study the functional role of CPNE1 in cellular processes by providing a platform where the gene's activity is eliminated, offering a unique approach to explore the implications of its absence in various biological contexts.

The primary function of CPNE1 is to act as a calcium-dependent phospholipid-binding protein, which is implicated in several cellular functions, including signal transduction, membrane trafficking, and cytoskeletal organization. By employing these knockout cell lines, scientists can investigate the physiological consequences of CPNE1 loss, including perturbations in cell signaling pathways and altered cellular responses to environmental stimuli. This mechanistic understanding is essential in elucidating the role of CPNE1 in disease processes such as cancer progression, neurodegenerative diseases, and developmental disorders.

In the realms of research and clinical applications, these knockout cell lines represent a valuable tool for gene function studies, drug screening, and the development of targeted therapeutic strategies. Their ability to mimic pathological conditions through specific gene knockouts allows for more accurate modeling of diseases which is critical for advancing medical research and therapeutic interventions.

Compared to traditional methods of gene silencing, such as siRNA or shRNA, CPNE1 Gene Knockout Cell Lines provide a stable and permanent solution to study gene functions, eliminating off-target effects often associated with transient approaches. Additionally, the production of these knockout lines ensures reproducibility and ease of use in experiments, making them a preferred choice for researchers.

For researchers, clinicians, and biotechnology professionals, the CPNE1 Gene Knockout Cell Lines from our company offer a robust and scientifically validated resource pivotal for cutting-edge research. With years of expertise in genetic engineering and a commitment to quality, our products are designed to empower scientific discovery, pushing the boundaries of knowledge in molecular biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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