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CPLX1 Knockout Cell Lines

Gene: CPLX1

Official Full Name: complexin 1provided by HGNC

Gene Summary: Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31485 CPLX1 Knockout cell line (HCT 116) Human CPLX1 1:2~1:4 Negative Online Inquiry
KO31486 CPLX1 Knockout cell line (HEK293) Human CPLX1 1:3~1:6 Negative Online Inquiry

Background

CPLX1 Gene Knockout Cell Lines are genetically modified cell lines in which the CPLX1 gene has been selectively inactivated, creating a powerful tool for investigating the biological functions and roles of this gene in various cellular processes. With the CPLX1 gene being implicated in synaptic regulation and neuronal function, these knockout cell lines enable researchers to dissect the molecular pathways and physiological effects associated with its absence.

The primary mechanism of action involves the deletion of the CPLX1 gene via CRISPR-Cas9 technology, ensuring a precise knockout with minimal off-target effects. This enables scientists to explore the implications of CPLX1 loss in a controlled environment, providing invaluable insights into synaptic dynamics, neurotransmitter release, and neurodevelopmental disorders. Moreover, these cell lines serve as a crucial model for examining how changes in CPLX1 expression may contribute to various pathologies, including neurodegenerative diseases and psychiatric disorders.

In research and clinical settings, the ability to analyze gene function using CPLX1 Gene Knockout Cell Lines is of paramount importance, especially for any studies focused on synaptic biology or related therapeutic approaches. Unlike traditional techniques, the knockdown of CPLX1 allows for complete gene inactivation, giving clarity to the contributions of this gene. This product stands apart from other gene editing tools due to its robustness, reproducibility, and the specificity of the gene deletion, allowing for consistent experimental results.

For researchers and clinicians, the value of CPLX1 Gene Knockout Cell Lines is clear: they facilitate groundbreaking studies that can reveal novel insights into fundamental biological processes and disease mechanisms. By employing these knockout cell lines, users can enhance their research efficacy and drive discoveries that may translate to innovative therapeutic strategies.

With a commitment to quality and innovation, our company leverages advanced genomic technologies to provide top-tier biological products, ensuring that researchers have the best tools at their disposal for scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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