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CPEB1 Knockout Cell Lines

Gene: CPEB1

Official Full Name: cytoplasmic polyadenylation element binding protein 1provided by HGNC

Gene Summary: This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18579 CPEB1 Knockout cell line (HEK293) Human CPEB1 1:3~1:6 Negative Online Inquiry
KO18580 CPEB1 Knockout cell line (A549) Human CPEB1 1:3~1:4 Negative Online Inquiry

Background

CPEB1 Gene Knockout Cell Lines are engineered cell lines that have had the cytoplasmic polyadenylation element binding protein 1 (CPEB1) gene inactivated, resulting in the loss of function of this critical RNA-binding protein. CPEB1 plays a pivotal role in the regulation of mRNA translation, stability, and polyadenylation, which are essential processes in controlling gene expression at the post-transcriptional level. By utilizing specific gene-editing technologies such as CRISPR-Cas9, these cell lines allow researchers to investigate the physiological and pathological roles of CPEB1 with unprecedented precision.

The key functions of CPEB1 include influencing neuronal development, synaptic plasticity, and cellular responses to stress, making these knockout cell lines invaluable for studying neurodegenerative diseases, cancer, and other cellular dysfunctions. With the depletion of CPEB1, researchers can explore altered pathways and interactions involved in these complex biological processes, leading to insights that may contribute to the development of novel therapeutic strategies.

The scientific importance of CPEB1 Gene Knockout Cell Lines extends across various research fields, including molecular biology, cancer research, and neurobiology. These cell lines serve as critical tools for understanding gene function and the biological impacts of post-transcriptional regulation in health and disease. Compared to traditional models, such as RNA interference or overexpression systems, knockout cell lines provide a robust and stable platform for validating the role of CPEB1 in complex cellular networks.

The unique selling points of CPEB1 Gene Knockout Cell Lines include their high specificity, reproducibility, and the ability to generate an environment that closely mimics in vivo conditions. These attributes enable researchers to conduct more accurate and reliable experiments, providing deeper insights into the molecular mechanisms underlying various biological phenomena.

For researchers and clinicians, the value of these cell lines lies in their application potential—not only as a tool for fundamental research but also for translational studies aimed at uncovering new therapeutic avenues. Equipped with a wealth of expertise in gene editing technologies and cell line development, our company is committed to offering high-quality biological products that empower the scientific community to advance knowledge and tackle pressing health challenges.

Please note that all services are for research use only. Not intended for any clinical use.

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