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CPA4 Knockout Cell Lines

Gene: CPA4

Official Full Name: carboxypeptidase A4provided by HGNC

Gene Summary: This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04194 CPA4 Knockout cell line (HeLa) Human CPA4 1:3~1:6 Negative Online Inquiry
KO04195 CPA4 Knockout cell line (HCT 116) Human CPA4 1:2~1:4 Negative Online Inquiry
KO04196 CPA4 Knockout cell line (A549) Human CPA4 1:3~1:4 Negative Online Inquiry

Background

CPA4 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene disruption to eliminate the expression of the CPA4 gene, which is implicated in various biological processes, including cancer progression and immune modulation. These cell lines serve as essential tools for investigating the physiological roles of CPA4 and its contribution to disease mechanisms.

The core function of CPA4 Gene Knockout Cell Lines involves their ability to act as model systems to study the loss-of-function effects associated with CPA4. Utilizing CRISPR-Cas9 technology, researchers can create precise gene knockouts, enabling the examination of resultant phenotypes, changes in cellular signaling pathways, and gene expression profiles. By providing insights into the cellular pathways influenced by the absence of CPA4, researchers can better understand its role in pathophysiology, particularly concerning tumor growth or immune response anomalies.

The scientific importance of these cell lines is underscored by their diverse applications in both research and clinical settings. They are indispensable for drug discovery processes, allowing scientists to screen potential therapeutics that target CPA4-related pathways, as well as evaluating the efficacy and safety of new treatment modalities. Furthermore, these cell lines serve as platforms for biomarker development and validation in clinical diagnostics.

What sets CPA4 Gene Knockout Cell Lines apart from alternative products is their targeted specificity and reliability. They are optimized for high performance, ensuring consistent results in experimental outcomes, which is crucial for experimental reproducibility and data integrity. Additionally, our comprehensive support in terms of documentation, user protocols, and scientific consultation further enhances their utility in biomedical research.

By integrating CPA4 Gene Knockout Cell Lines into their research, scientists and clinicians stand to gain a sophisticated understanding of disease mechanisms, paving the way for innovative therapeutic strategies. Our company, with its extensive expertise in genetic engineering and a commitment to advancing scientific discovery, is dedicated to providing high-quality biological products that facilitate groundbreaking research and improve healthcare outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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