Gene: COPS7A
Official Full Name: COP9 signalosome subunit 7Aprovided by HGNC
Gene Summary: This gene encodes a component of the COP9 signalosome, an evolutionarily conserved multi-subunit protease that regulates the activity of the ubiquitin conjugation pathway. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23294 | COPS7A Knockout cell line (HeLa) | Human | COPS7A | 1:3~1:6 | Negative | Online Inquiry |
KO23295 | COPS7A Knockout cell line (HCT 116) | Human | COPS7A | 1:2~1:4 | Negative | Online Inquiry |
KO23296 | COPS7A Knockout cell line (HEK293) | Human | COPS7A | 1:3~1:6 | Negative | Online Inquiry |
KO23297 | COPS7A Knockout cell line (A549) | Human | COPS7A | 1:3~1:4 | Negative | Online Inquiry |
COPS7A Gene Knockout Cell Lines are specifically engineered cell lines that have been designed to lack the COPS7A gene, which plays a critical role in various cellular processes, particularly in the regulation of proteostasis and signaling pathways. These knockout cell lines are invaluable tools for studying the biological functions of the COPS7A gene and its implications in health and disease.
The key function of COPS7A is its involvement in the COP9 signalosome, a multi-protein complex essential for regulating protein degradation and modulating key signaling pathways. The knockout of this gene allows researchers to dissect the underlying mechanisms by which COPS7A influences cellular response to stress, development, and tumorigenesis. By using COPS7A knockout cell lines, researchers can experimentally manipulate this critical regulatory network, facilitating the discovery of novel therapeutic targets and enhancing our understanding of pathophysiological conditions.
The scientific importance of COPS7A Gene Knockout Cell Lines extends to various research fields, including cancer biology, neurobiology, and developmental biology. In clinical settings, these cell lines can be applied in drug screening assays to identify compounds that may restore normal signaling pathways or mitigate disease outcomes associated with COPS7A dysregulation.
One of the unique advantages of COPS7A Gene Knockout Cell Lines over traditional knocking down techniques, such as siRNA, is the stable and permanent alteration of the gene, which allows for long-term studies without the concern of transient effects. Furthermore, these cell lines provide a robust platform for reproducibility, allowing for high-confidence data generation.
Given their precise genetic modification and the broad applicability in cutting-edge research, COPS7A Gene Knockout Cell Lines are invaluable for researchers and clinicians aiming to unravel complex biological questions or develop new therapeutic strategies. Our company prides itself on delivering high-quality biological products, and our expertise ensures that these cell lines meet the rigorous standards necessary for impactful research and experimentation.
Please note that all services are for research use only. Not intended for any clinical use.
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