Home / COBL Knockout Cell Lines

COBL Knockout Cell Lines

Gene: COBL

Official Full Name: cordon-bleu WH2 repeat proteinprovided by HGNC

Gene Summary: This gene encodes a protein that contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. The encoded actin regulator protein is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure. A pseudogene of this gene is located on chromosome X. [provided by RefSeq, Oct 2016]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29630 COBL Knockout cell line (HeLa) Human COBL 1:3~1:6 Negative Online Inquiry
KO29631 COBL Knockout cell line (HCT 116) Human COBL 1:2~1:4 Negative Online Inquiry
KO29632 COBL Knockout cell line (HEK293) Human COBL 1:3~1:6 Negative Online Inquiry
KO29633 COBL Knockout cell line (A549) Human COBL 1:3~1:4 Negative Online Inquiry

Background

COBL Gene Knockout Cell Lines are genetically modified cellular models designed for the investigation of gene function and disease mechanisms through targeted gene disruption. These cell lines specifically target the COBL gene, which plays a critical role in various biological processes, including cell differentiation and cytoskeletal organization. By employing CRISPR-Cas9 technology, the COBL Gene Knockout Cell Lines allow for precise editing of the genome, rendering the gene inoperative and facilitating a comprehensive study of its effects on cellular physiology.

The key functions of these cell lines lie in their ability to mimic disease states or specific biological conditions by elucidating the roles of the COBL gene in cellular behavior. Researchers can conduct experiments on cellular growth, migration, and response to stimuli, thus revealing the impacts of gene loss on various pathways. This mechanistic insight is crucial for advancing our understanding of genetic contributions to diseases, particularly in cancer and other conditions where gene dysfunction is involved.

The scientific importance of COBL Gene Knockout Cell Lines extends to both basic research and clinical applications. In translational research, these cell lines serve as invaluable tools for drug discovery and efficacy assessments, enabling researchers to test therapeutic approaches targeting pathways influenced by the COBL gene. The potential to bridge the gap between laboratory findings and clinical outcomes enhances their value to both academic and pharmaceutical research contexts.

One of the unique selling points of COBL Gene Knockout Cell Lines is their ease of use and reproducibility, ensuring that results are reliable and can be compared across different studies. Unlike conventional gene knockout methods that can be labor-intensive and time-consuming, the CRISPR-Cas9 approach used in generating these cell lines streamlines the process, significantly reducing the turnaround time for experiments. Furthermore, these cell lines are rigorously characterized and validated, offering users confidence in their experimental robustness.

For researchers and clinicians alike, the value of COBL Gene Knockout Cell Lines lies not only in their innovative design but also in their potential to accelerate discoveries in genetic research and therapeutic development. Utilizing these advanced cell lines can lead to breakthroughs in understanding complex gene interactions and disease mechanisms.

Our company is dedicated to providing high-quality biological reagents and solutions, bolstered by our expertise in genetic modification technologies and a commitment to supporting researchers with cutting-edge tools to drive their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.