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CNRIP1 Knockout Cell Lines

Gene: CNRIP1

Official Full Name: cannabinoid receptor interacting protein 1provided by HGNC

Gene Summary: This gene encodes a protein that interacts with the C-terminal tail of cannabinoid receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28608 CNRIP1 Knockout cell line (HeLa) Human CNRIP1 1:3~1:6 Negative Online Inquiry
KO28609 CNRIP1 Knockout cell line (HEK293) Human CNRIP1 1:3~1:6 Negative Online Inquiry

Background

CNRIP1 Gene Knockout Cell Lines are genetically engineered cells wherein the CNRIP1 (Calcium- and Voltage-Activated Potassium Channels Interacting Protein 1) gene has been deliberately ablated. This innovative biological product serves as a powerful tool for elucidating the role of CNRIP1 in various signaling pathways and cellular processes. By removing the expression of this gene, researchers can create an in vitro model that closely approximates the physiological effects observed when CNRIP1 is inactive, thereby allowing for targeted studies into its functions and interactions.

The knockout mechanism involves the use of CRISPR/Cas9 technology, which introduces specific double-strand breaks in the DNA, thus enabling precise gene editing. Following repair mechanisms, the CNRIP1 gene is disrupted, resulting in cellular phenotypes that can be analyzed for alterations in proliferation, differentiation, and metabolic activity. These cell lines can be utilized in a variety of assays, including drug efficacy studies, gene therapy exploration, and biomarker identification, making them indispensable in both research and clinical settings.

The scientific importance of CNRIP1 Gene Knockout Cell Lines cannot be overstated, as they offer novel insights into calcium signaling, neural function, and potential implications in neurological disorders. Unlike RNA interference methods, which may result in only transient reduction of gene expression, our knockout cells provide a stable, long-term solution for studying gene function and its implications in pathophysiology.

Unique selling points of our product include extensive characterization and validation through genomic sequencing and functional assays, ensuring reliability and reproducibility in experiments. Researchers and clinicians alike will benefit from enhanced experimental rigor and the ability to derive meaningful data from these highly specialized cell lines.

Our commitment to advancing biological research is reflected in our expertise, state-of-the-art facilities, and continuous pursuit of excellence. By providing cutting-edge products like the CNRIP1 Gene Knockout Cell Lines, we empower researchers and clinicians to uncover new scientific insights and translate these findings into actionable medical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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