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CNOT10 Knockout Cell Lines

Gene: CNOT10

Official Full Name: CCR4-NOT transcription complex subunit 10provided by HGNC

Gene Summary: Predicted to be involved in mRNA catabolic process and negative regulation of translation. Located in membrane. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28653 CNOT10 Knockout cell line (HeLa) Human CNOT10 1:3~1:6 Negative Online Inquiry
KO28654 CNOT10 Knockout cell line (HCT 116) Human CNOT10 1:2~1:4 Negative Online Inquiry
KO28655 CNOT10 Knockout cell line (HEK293) Human CNOT10 1:3~1:6 Negative Online Inquiry
KO28656 CNOT10 Knockout cell line (A549) Human CNOT10 1:3~1:4 Negative Online Inquiry

Background

CNOT10 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the study of gene function and regulation in a controlled environment. By utilizing CRISPR-Cas9 technology, these cell lines have been precisely created to knock out the CNOT10 gene, a crucial component of the CCR4-NOT complex involved in mRNA degradation and transcriptional regulation. The knockout of CNOT10 allows researchers to delve into the mechanisms by which gene expression is modulated, providing insights into cellular processes such as differentiation, proliferation, and response to environmental stimuli.

The key function of the CNOT10 Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function scenarios, offering a versatile platform for studying the implications of CNOT10 ablation at both the molecular and phenotypic levels. This functionality is pivotal in research aimed at understanding diseases characterized by dysregulated mRNA turnover or aberrant gene expression, including various cancers and neurodegenerative disorders.

The scientific importance of these cell lines extends to their applications in drug discovery and therapeutic research. By providing a reliable model to assess the effects of pharmacological agents on cellular dynamics pertaining to CNOT10, these knockout lines facilitate the identification of potential biomarkers and targets for intervention. Moreover, they serve as essential tools in the validation of genetic interactions and pathways implicated in health and disease.

What distinguishes CNOT10 Gene Knockout Cell Lines from alternative models is their robust reproducibility, offering researchers consistent outcomes in experimental workflows. Additionally, these cell lines are compatible with high-throughput screening processes, making them an efficient choice for labs focused on large-scale genetic studies.

The value of CNOT10 Gene Knockout Cell Lines to researchers and clinicians lies not only in their utility for fundamental biological research but also in their potential to bridge the gap between basic science and clinical applications. These cell lines empower scientific investigations that could translate into novel therapeutic strategies.

Our company, with its strong foundation in genetic engineering and cell line development, is committed to providing high-quality biological products that enhance research outcomes and drive innovation in the life sciences field.

Please note that all services are for research use only. Not intended for any clinical use.

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