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CNNM3 Knockout Cell Lines

Gene: CNNM3

Official Full Name: cyclin and CBS domain divalent metal cation transport mediator 3provided by HGNC

Gene Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in magnesium ion homeostasis. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28092 CNNM3 Knockout cell line (HeLa) Human CNNM3 1:3~1:6 Negative Online Inquiry
KO28093 CNNM3 Knockout cell line (HCT 116) Human CNNM3 1:2~1:4 Negative Online Inquiry
KO28094 CNNM3 Knockout cell line (HEK293) Human CNNM3 1:3~1:6 Negative Online Inquiry
KO28095 CNNM3 Knockout cell line (A549) Human CNNM3 1:3~1:4 Negative Online Inquiry

Background

CNNM3 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the expression of the CNNM3 gene, a member of the cyclin family implicated in various physiological and pathophysiological processes. These cell lines are invaluable tools for researchers investigating the functional role of CNNM3 in cellular mechanisms, including magnesium transport and potential links to metabolic diseases. The knockout of the CNNM3 gene allows for the exploration of its contributions to cellular signaling pathways, which could elucidate broader implications in human health and disease states.

The primary mechanism of the CNNM3 knockout involves the use of targeted gene-editing techniques, such as CRISPR-Cas9, enabling precise modifications to the genomic DNA. By creating a loss-of-function model, researchers can study the phenotypic consequences of CNNM3 absence, allowing for detailed analyses of cellular behaviors, interactions, and metabolic profiles. These insights are pivotal in both basic research and the development of therapeutic strategies.

From a scientific standpoint, CNNM3 Gene Knockout Cell Lines offer critical applications in pharmacology, genetics, and personalized medicine. They facilitate drug discovery processes by providing a platform to screen for compounds that may alter disease pathways linked to CNNM3 dysfunction. Additionally, the ability to explore gene-environment interactions in these models can enhance our understanding of disease susceptibility and contribute to targeted interventions.

Compared to traditional cell lines, the specificity and efficiency of CNNM3 knockout models provide a significant advantage. They eliminate confounding variables associated with partial gene silencing or overexpression, leading to more reliable and reproducible experimental outcomes. This high level of specificity allows for the generation of insights that are directly applicable to human biology, enhancing the translational potential of research findings.

For researchers and clinicians, investing in CNNM3 Gene Knockout Cell Lines means obtaining a powerful and precise tool for probing the depths of gene functionality and disease mechanisms. These models empower the scientific community to advance our understanding of critical biological processes and develop innovative therapeutic solutions.

With a track record of excellence in genetic engineering and cell line development, our company is committed to providing cutting-edge biological products that enable meaningful research and foster scientific advancements. We stand ready to support your research needs with our expertly developed offerings that adhere to the highest standards of quality and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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