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CNN1 Knockout Cell Lines

Gene: CNN1

Official Full Name: calponin 1provided by HGNC

Gene Summary: Predicted to enable actin filament binding activity. Involved in negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07307 CNN1 Knockout cell line (HeLa) Human CNN1 1:3~1:6 Negative Online Inquiry
KO07308 CNN1 Knockout cell line (A549) Human CNN1 1:3~1:4 Negative Online Inquiry

Background

CNN1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the CNN1 gene, which encodes the protein Cyclin N1. These cell lines are pivotal tools in molecular biology and genetic research, allowing scientists to study the functional implications of CNN1 across various biological processes, including cell cycle regulation and differentiation.

The primary mechanism by which CNN1 Gene Knockout Cell Lines operate involves the selective deletion of the CNN1 gene, leading to an absence of the associated protein in cellular systems. This knockout effect allows researchers to elucidate the gene's role in essential cellular functions, including proliferation, migration, and apoptosis. By comparing these modified cells to their wild-type counterparts, scientists can gain insights into the regulatory pathways that CNN1 influences and its potential involvement in various diseases, including cancers.

The scientific importance of these cell lines extends to both research and clinical applications. In research settings, they serve as invaluable models for investigating the pathophysiology of disorders related to cell cycle dysregulation. Clinically, understanding the role of CNN1 may pave the way for developing targeted therapies against related malignancies. Their specific applications could range from drug screening to genetic interaction studies, making them highly versatile tools in a researcher's arsenal.

One of the primary advantages of CNN1 Gene Knockout Cell Lines lies in their specificity and reproducibility. Unlike traditional experimental methods that may be confounded by off-target effects, these knockouts provide a clear and defined system to study the consequences of gene loss. Additionally, our product is characterized by rigorous quality control and validation processes, ensuring that users receive reliable and consistent results in their experiments.

For researchers and clinicians alike, CNN1 Gene Knockout Cell Lines represent an essential resource that fosters detailed investigations into gene function and disease mechanisms. Their development is backed by our company’s expertise in genetic engineering and cell biology, underscoring our commitment to providing high-quality, innovative products that support cutting-edge scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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