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CMTM8 Knockout Cell Lines

Gene: CMTM8

Official Full Name: CKLF like MARVEL transmembrane domain containing 8provided by HGNC

Gene Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21842 CMTM8 Knockout cell line (HeLa) Human CMTM8 1:3~1:6 Negative Online Inquiry
KO21843 CMTM8 Knockout cell line (HCT 116) Human CMTM8 1:2~1:4 Negative Online Inquiry
KO21844 CMTM8 Knockout cell line (HEK293) Human CMTM8 1:3~1:6 Negative Online Inquiry
KO21845 CMTM8 Knockout cell line (A549) Human CMTM8 1:3~1:4 Negative Online Inquiry

Background

CMTM8 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the CMTM8 gene, which is implicated in various biological processes including cell proliferation, differentiation, and immune response modulation. These knockout cell lines are created using precision gene-editing technologies, allowing for the deletion of CMTM8 expression, thus providing a robust system for researchers aiming to elucidate the gene's function in both normal and pathological contexts.

The key function of CMTM8 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for investigating the effects of CMTM8 loss on cellular behavior. By utilizing these cell lines, researchers can explore alterations in signaling pathways, evaluate changes in protein interactions, and assess how the absence of CMTM8 influences cellular responses to stimuli. The mechanistic insights gained from these studies are invaluable for understanding the gene's role in diseases, particularly those involving immune dysregulation or tumorigenesis.

From a scientific standpoint, the availability of CMTM8 Gene Knockout Cell Lines has significant implications for both research and clinical applications. They serve as essential tools in the development of targeted therapies and novel drug discovery initiatives, particularly in cancer immunotherapy. Understanding the function of the CMTM8 gene can shed light on potential therapeutic targets and lead to the creation of more effective treatment strategies.

What sets our CMTM8 Gene Knockout Cell Lines apart from alternatives is their high fidelity and reproducibility, characterized by reliable knockout efficiency and consistent cell line performance. These features markedly enhance experimental reliability and facilitate easier comparison across studies, effectively reducing variability often encountered with conventional models.

For researchers and clinicians, these cell lines represent an invaluable addition to their toolkit, offering the opportunity to advance their investigations into gene function and its implications in health and disease. By choosing CMTM8 Gene Knockout Cell Lines, professionals gain access to expertly crafted models that empower meaningful discoveries.

Our company specializes in the development and provision of innovative biological products, and we are dedicated to supporting researchers with high-quality tools that drive scientific advancement and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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