Gene: CLPTM1L
Official Full Name: CLPTM1 likeprovided by HGNC
Gene Summary: The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25840 | CLPTM1L Knockout cell line (HeLa) | Human | CLPTM1L | 1:3~1:6 | Negative | Online Inquiry |
KO25841 | CLPTM1L Knockout cell line (HCT 116) | Human | CLPTM1L | 1:2~1:4 | Negative | Online Inquiry |
KO25842 | CLPTM1L Knockout cell line (HEK293) | Human | CLPTM1L | 1:3~1:6 | Negative | Online Inquiry |
KO25843 | CLPTM1L Knockout cell line (A549) | Human | CLPTM1L | 1:3~1:4 | Negative | Online Inquiry |
CLPTM1L Gene Knockout Cell Lines are precisely engineered cellular models designed to study the functional consequences of CLPTM1L gene deletion. The CLPTM1L gene plays a pivotal role in the regulation of cellular processes, including apoptosis and response to oxidative stress, making it crucial for understanding various pathological conditions, such as cancer and neurodegenerative diseases. By utilizing these knockout cell lines, researchers can effectively assess the gene's contributions to cellular mechanisms, enabling them to elucidate its role in disease etiology and therapeutic response.
The mechanisms by which CLPTM1L knockout cell lines function hinge on the complete disruption of the gene's expression, thus allowing for the observation of phenotype alterations in comparison to wild-type cell lines. This approach facilitates targeted studies into gene function, cellular signaling pathways, and the physiological impact of gene loss. It also aids in revealing potential biomarkers for disease and therapeutic targets.
The scientific importance of CLPTM1L Gene Knockout Cell Lines extends across both research and clinical settings, providing a valuable resource for cancer research, drug development, and the exploration of genetic diseases. The unique advantages of these cell lines lie in their specificity and reliable reproducibility, which are critical for advancing translational research initiatives. Researchers often face challenges with off-target effects and variability in gene editing, but our proprietary knockout technology ensures precision and consistency unmatched by alternative models.
This product holds tremendous value for researchers and clinicians alike, as it equips them with a robust tool to unlock the complexities of gene function in a controlled environment. Through the elucidation of critical biological pathways associated with CLPTM1L, users gain insights that can drive innovation in treatment strategies and contribute to advancements in personalized medicine.
Harnessing years of expertise in genetic engineering and cell line development, our company stands at the forefront of providing high-quality biological products. We are committed to supporting the scientific community with tools that enhance research efficiency and promote breakthroughs in understanding human health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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