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CLGN Knockout Cell Lines

Gene: CLGN

Official Full Name: calmeginprovided by HGNC

Gene Summary: Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38599 CLGN Knockout cell line (HeLa) Human CLGN 1:3~1:6 Negative Online Inquiry
KO38600 CLGN Knockout cell line (HCT 116) Human CLGN 1:2~1:4 Negative Online Inquiry
KO38601 CLGN Knockout cell line (HEK293) Human CLGN 1:3~1:6 Negative Online Inquiry
KO38602 CLGN Knockout cell line (A549) Human CLGN 1:3~1:4 Negative Online Inquiry

Background

CLGN Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the functional CLGN gene, which encodes for a protein implicated in various cellular processes including cell signaling, proliferation, and differentiation. By utilizing CRISPR-Cas9 technology, these cell lines provide a robust platform for studying the gene's role in health and disease, allowing researchers to investigate the mechanisms underlying various biological phenomena in a controlled environment.

The primary function of the CLGN knockout cell lines is to facilitate the elucidation of the effects of gene loss on cellular behavior and molecular pathways. By comparing knockout cells to wild-type counterparts, researchers can assess changes in gene expression profiles, signaling cascades, and cellular responses to different stimuli. Such insights are crucial for understanding diseases where CLGN is implicated, including certain cancers and metabolic disorders.

In research and clinical settings, CLGN Gene Knockout Cell Lines hold significant potential for drug discovery, functional genomics, and personalized medicine. They provide a reliable model for screening therapeutic compounds aimed at restoring normal function in cases where CLGN expression is dysregulated. Moreover, these cell lines can aid in understanding the genetic bases of specific diseases, thereby contributing to the development of targeted interventions.

What sets CLGN Gene Knockout Cell Lines apart from alternatives is their rigorously validated genetic modification, ensuring high specificity and reliability in experimental outcomes. Additionally, they undergo extensive characterization to confirm the absence of the CLGN protein and any compensatory mutations or effects, making them a gold standard in gene knockout research.

Researchers and clinicians will find immense value in utilizing CLGN Gene Knockout Cell Lines, as they pave the way for groundbreaking discoveries and the development of innovative therapeutic strategies. By integrating these models into their studies, users can enhance the accuracy and relevance of their findings, ultimately expediting advancements in biomedical science.

Our company demonstrates a deep expertise in genetic engineering and cell biology. We are committed to providing high-quality biological products that empower researchers and contribute to the global scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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