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CLEC10A Knockout Cell Lines

Gene: CLEC10A

Official Full Name: C-type lectin domain containing 10Aprovided by HGNC

Gene Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00147 CLEC10A Knockout cell line (THP-1) Human CLEC10A 1:2-1:4 Negative Online Inquiry

Background

CLEC10A Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the CLEC10A gene, which encodes a C-type lectin receptor associated with immune responses and potential therapeutic targets in various diseases. These knockout cell lines have been genetically engineered to lack functional CLEC10A protein, thus allowing researchers to investigate the specific functions and pathways influenced by this receptor in both physiological and pathological contexts.

The key functions of CLEC10A include its role in the recognition of pathogens, regulation of innate immunity, and modulation of cell signaling. By utilizing these knockout cell lines, scientists can assess the receptor's contributions to immune cell activation, cytokine production, and interaction with other immune components. The precise mechanisms underlying CLEC10A interactions can be elucidated using a variety of assays, from flow cytometry to gene expression analysis, thus providing comprehensive insights into its biological roles.

The scientific importance of using CLEC10A Gene Knockout Cell Lines transcends basic research; they hold significant applications in clinical settings, particularly in disease models related to cancer, autoimmunity, and infectious diseases. Understanding the functions of CLEC10A may lead to the development of novel immunotherapies and targeted treatments, enhancing the effectiveness of current therapeutic strategies.

Compared to other gene knockout models, our CLEC10A cell lines offer superior specificity and reliability due to their thorough validation and characterization process. Users benefit from a streamlined approach to studying complex biological processes with reduced variability and increased reproducibility in their experiments.

For researchers and clinicians focused on the cutting-edge areas of immunology and therapeutics, these knockout cell lines represent a valuable tool that can accelerate discoveries and improve translational outcomes. Our commitment to high-quality biological products and extensive expertise in genetic engineering ensures that you receive exceptional models that stand up to rigorous scientific scrutiny and enhance your research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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