Gene: CLDND2
Official Full Name: claudin domain containing 2provided by HGNC
Gene Summary: Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27508 | CLDND2 Knockout cell line (HeLa) | Human | CLDND2 | 1:3~1:6 | Negative | Online Inquiry |
KO27509 | CLDND2 Knockout cell line (HEK293) | Human | CLDND2 | 1:3~1:6 | Negative | Online Inquiry |
KO27510 | CLDND2 Knockout cell line (A549) | Human | CLDND2 | 1:3~1:4 | Negative | Online Inquiry |
CLDND2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the CLDND2 gene, a critical player in lipid metabolism and cellular signaling pathways. These cell lines have been meticulously developed using CRISPR-Cas9 technology to ensure precise and efficient gene disruption, allowing researchers to delve into the biological roles and implications of CLDND2 in various physiological and pathological contexts.
The key function of CLDND2 knockout cell lines lies in their ability to facilitate investigations into lipid bilayer dynamics, cellular responses to stressors, and the gene's contribution to neurodegenerative diseases and cancer. By observing the functional consequences of CLDND2 deficiency, scientists can uncover intricate mechanisms underlying disease progression and identify potential therapeutic targets.
In research and clinical settings, these cell lines serve as invaluable tools for drug discovery, biomarker validation, and mechanistic studies. Their versatility enables their application in a multitude of research disciplines, from cancer biology to metabolic disorders, reinforcing the significance of CLDND2 in maintaining cellular homeostasis.
Compared to conventional cell lines, CLDND2 knockout cell lines offer enhanced specificity and relevance for studies focusing on lipid metabolism and its associated disorders, making them superior models for understanding complex biological processes. Their unique characteristic of complete gene disruption allows for clearer interpretation of phenotypic changes, thereby providing more reliable data for experimental validation.
For researchers and clinicians, the value of utilizing CLDND2 knockout cell lines cannot be overstated. The in-depth insights gleaned from these models not only advance our understanding of fundamental biology but also pave the way for novel therapeutic strategies in age-associated and metabolic diseases. Our company's expertise in gene editing technologies and commitment to high-quality biological products ensures that you receive reliable and reproducible cell lines tailored to your research needs. By leveraging our advanced offerings, you can drive your studies forward with confidence in the integrity and applicability of your experimental models.
Please note that all services are for research use only. Not intended for any clinical use.
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