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CIP2A Knockout Cell Lines

Gene: CIP2A

Official Full Name: cellular inhibitor of PP2Aprovided by HGNC

Gene Summary: Enables protein homodimerization activity and protein phosphatase inhibitor activity. Involved in broken chromosome clustering. Located in cytosol and plasma membrane. Is active in chromosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20916 CIP2A Knockout cell line (HeLa) Human CIP2A 1:3~1:6 Negative Online Inquiry
KO20917 CIP2A Knockout cell line (HCT 116) Human CIP2A 1:2~1:4 Negative Online Inquiry
KO20918 CIP2A Knockout cell line (HEK293) Human CIP2A 1:3~1:6 Negative Online Inquiry
KO20919 CIP2A Knockout cell line (A549) Human CIP2A 1:3~1:4 Negative Online Inquiry

Background

CIP2A Gene Knockout Cell Lines are genetically engineered cell lines in which the CIP2A gene has been selectively disrupted, resulting in the loss of its protein expression. CIP2A (Cancerous Inhibitor of Protein Phosphatase 2A) is known for its role in regulating various cellular processes related to cancer progression, including cell proliferation, survival, and differentiation. By utilizing these knockout cell lines, researchers can effectively study the specific pathways and biological functions associated with CIP2A, allowing for a deeper understanding of its role in oncogenesis and tumor biology.

The key mechanism behind the utility of these cell lines lies in their ability to provide a controlled environment for experiments aimed at elucidating the effects of CIP2A loss on cellular behavior. This includes investigating altered signaling pathways, changes in apoptotic responses, and differential gene expression profiles, which can all be critical for the development of targeted cancer therapies. Additionally, these cell lines serve as powerful models for testing the efficacy of potential therapeutic agents and understanding drug resistance mechanisms.

The scientific importance of CIP2A Gene Knockout Cell Lines cannot be overstated, particularly in the context of translational research and drug discovery. These cell lines are relevant in diverse research applications, including cancer biology, molecular pathology, and therapeutic development. By facilitating robust in vitro studies, they empower researchers to generate insights that may lead to novel treatment strategies and biomarker identification, thus directly impacting clinical outcomes.

What sets our CIP2A Gene Knockout Cell Lines apart from alternative products is their validated genetic modification, high growth viability, and reproducibility across various research settings. Our commitment to quality ensures that each cell line is rigorously screened, providing researchers with a reliable tool that enhances the accuracy of their experiments.

Our product’s unique value to researchers and clinicians lies in its capacity to advance understanding of cancer biology, ultimately contributing to the improvement of patient care through innovative treatments. With extensive experience in the development of biological products, our company stands as a trusted partner in pushing the boundaries of scientific discovery and clinical application.

Please note that all services are for research use only. Not intended for any clinical use.

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