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CHCHD6 Knockout Cell Lines

Gene: CHCHD6

Official Full Name: coiled-coil-helix-coiled-coil-helix domain containing 6provided by HGNC

Gene Summary: Involved in DNA damage response and cristae formation. Located in cytosol and mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05580 CHCHD6 Knockout cell line (HeLa) Human CHCHD6 1:3~1:6 Negative Online Inquiry
KO05581 CHCHD6 Knockout cell line (HCT 116) Human CHCHD6 1:2~1:4 Negative Online Inquiry
KO05582 CHCHD6 Knockout cell line (HEK293) Human CHCHD6 1:3~1:6 Negative Online Inquiry
KO05583 CHCHD6 Knockout cell line (A549) Human CHCHD6 1:3~1:4 Negative Online Inquiry

Background

CHCHD6 Gene Knockout Cell Lines are specialized cellular models designed to study the functional implications of the CHCHD6 gene, which encodes a protein primarily involved in mitochondrial protein import and oxidative stress response. These knockout cell lines effectively eliminate the expression of the CHCHD6 gene, enabling researchers to investigate the biological processes and signaling pathways affected by its absence. The key function of these cell lines lies in their ability to replicate the downstream effects of CHCHD6 loss, thus serving as a crucial tool for understanding mitochondrial dynamics, cellular metabolism, and cellular responses to oxidative stress.

The scientific importance of CHCHD6 Gene Knockout Cell Lines extends to both basic and applied research settings. By utilizing these models, scientists can unravel the gene's role in various pathophysiological conditions, including neurodegenerative diseases and metabolic disorders. These cell lines provide a platform for high-throughput screening of potential therapeutic compounds, offering insights into drug efficacy and safety profiles. In clinical contexts, understanding the implications of CHCHD6 gene loss could lead to novel therapeutic targets or biomarkers for disease progression.

Compared to alternative methods such as transient gene silencing or wild-type cell lines, CHCHD6 Gene Knockout Cell Lines offer stable and reproducible results, enabling long-term studies without the variability associated with transient expressions. Furthermore, these knockout lines facilitate the establishment of isogenic models, enhancing the reliability of experimental outcomes.

For researchers, clinicians, and pharmaceutical companies, the value of these cell lines is evident. They represent a significant advancement in elucidating the CHCHD6 gene's role in health and disease, fostering innovation in therapeutic development and disease understanding. Our company specializes in providing high-quality biological products, including precisely engineered knockout cell lines, underpinned by robust scientific expertise and a commitment to advancing research in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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