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CHCHD5 Knockout Cell Lines

Gene: CHCHD5

Official Full Name: coiled-coil-helix-coiled-coil-helix domain containing 5provided by HGNC

Gene Summary: Predicted to be involved in cellular respiration. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25010 CHCHD5 Knockout cell line (HeLa) Human CHCHD5 1:3~1:6 Negative Online Inquiry
KO25011 CHCHD5 Knockout cell line (HCT 116) Human CHCHD5 1:2~1:4 Negative Online Inquiry
KO25012 CHCHD5 Knockout cell line (HEK293) Human CHCHD5 1:3~1:6 Negative Online Inquiry
KO25013 CHCHD5 Knockout cell line (A549) Human CHCHD5 1:3~1:4 Negative Online Inquiry

Background

CHCHD5 Gene Knockout Cell Lines are specialized cellular models created to facilitate the study of the CHCHD5 gene’s function and its implications in various biological processes. This product is developed using advanced CRISPR/Cas9 genome-editing technology, allowing for precision targeting and disruption of the CHCHD5 gene. The resultant cell lines exhibit a complete knockout of the gene, providing researchers with a valuable tool to dissect the role of CHCHD5 in pathways such as mitochondrial dynamics, apoptosis, and cellular response to stressors.

The primary function of these knockout cell lines is to enable scientists to study the effects of CHCHD5 loss on cellular metabolism and overall cell health. By investigating the mechanistic pathways altered in the absence of CHCHD5, researchers can uncover critical insights related to mitochondrial dysfunction, neurodegenerative diseases, and potential cancer pathways. Additionally, these cell lines serve as an effective platform for testing therapeutic candidates that may target the pathways influenced by CHCHD5, thus proving advantageous in both basic and translational research contexts.

Compared to alternatives such as RNA interference methods, which offer transient gene silencing, our CHCHD5 Gene Knockout Cell Lines provide a stable and permanent genetic alteration. This stability facilitates repeatable experiments and long-term studies, ensuring consistency in data collection. Furthermore, our cells are readily characterized and validated, reducing the time and effort required for preliminary testing.

For researchers and clinicians dedicated to unraveling the complexities of cellular function and disease mechanisms, the CHCHD5 Gene Knockout Cell Lines represent a cutting-edge solution. This product not only enhances experimental reliability but also accelerates the journey from discovery to therapeutic application. Our company prides itself on being at the forefront of biological product innovations, leveraging extensive expertise in genome editing and cell line development to support the scientific community in achieving groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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