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CHAD Knockout Cell Lines

Gene: CHAD

Official Full Name: chondroadherinprovided by HGNC

Gene Summary: Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in chondrocytes at all ages. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38576 CHAD Knockout cell line (HEK293) Human CHAD 1:3~1:6 Negative Online Inquiry

Background

CHAD Gene Knockout Cell Lines are genetically engineered cell models specifically designed to facilitate the study of CHAD (Chondrocyte and Homologous Gene) at the molecular and cellular levels. These cell lines have undergone targeted gene disruption techniques, such as CRISPR-Cas9, allowing for the complete knockout of the CHAD gene, providing researchers with a powerful tool to investigate the gene's functional role in various biological processes, particularly in cartilage development and pathology.

The key function of CHAD Gene Knockout Cell Lines lies in their ability to simulate the absence of CHAD expression, thus enabling the examination of cellular phenotypes, signaling pathways, and biochemical changes resulting from the gene's removal. Researchers can employ these cell lines to elucidate mechanisms underlying cartilage formation, apoptosis, and related disorders such as osteoarthritis and chondrodysplasia. By using these models, the assessment of potential therapeutic strategies targeting CHAD becomes more feasible, supporting both academic and clinical pursuits.

The scientific importance of CHAD Gene Knockout Cell Lines extends into numerous applications in research and translational medicine. In addition to their utility in basic research, these cell lines can serve as a basis for drug screening processes focused on cartilage-related diseases. They provide unparalleled insights into gene function and disease mechanisms, which is essential for advancing therapeutic development.

What differentiates CHAD Gene Knockout Cell Lines from alternative models is the precision of gene editing employed and the well-characterized nature of the knockout phenotype. This specificity, combined with the high reproducibility of results, positions these cell lines as reliable models for in-depth studies. Additionally, they are provided with comprehensive protocols for handling and experimentation, simplifying the process for researchers.

This product is invaluable to researchers and clinicians who are investigating the genetic underpinnings of cartilage-related disorders, providing a concrete foundation for novel therapeutic explorations. By integrating CHAD Gene Knockout Cell Lines into their workflows, scientists can gain meaningful insights that ultimately lead to better understanding and treatment of debilitating conditions.

Our company has a strong background in developing advanced biological products backed by rigorous scientific research and innovation. We are committed to supporting researchers with high-quality tools that propel discovery and enhance preclinical investigations, ensuring that scientists can unravel complex biological questions with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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