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CGA Knockout Cell Lines

Gene: CGA

Official Full Name: glycoprotein hormones, alpha polypeptideprovided by HGNC

Gene Summary: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07597 CGA Knockout cell line (HeLa) Human CGA 1:3~1:6 Negative Online Inquiry
KO07598 CGA Knockout cell line (HEK293) Human CGA 1:3~1:6 Negative Online Inquiry

Background

CGA Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of gene function and elucidate biological pathways associated with the CGA gene. By employing state-of-the-art CRISPR-Cas9 gene editing technology, these cell lines are created to effectively silence the CGA gene, thus enabling researchers to investigate the phenotypic and molecular consequences of gene depletion in various biological contexts.

The primary function of CGA Gene Knockout Cell Lines is to serve as a reference tool for assessing the impact of CGA gene loss on cellular behavior and related pathways. This is particularly critical in understanding disorders associated with altered CGA expression, such as certain neuroendocrine tumors or endocrine dysfunctions. Additionally, these knockout models are invaluable for drug discovery and toxicology studies, providing insights into potential therapeutic targets and mechanisms of action.

In research and clinical settings, CGA Gene Knockout Cell Lines play a vital role in dissecting complex biological mechanisms, offering high specificity in gene targeting that surpasses traditional RNA interference methods. They allow researchers to generate reproducible results with a precise understanding of gene roles, thereby advancing both basic biological research and applied biomedical sciences.

One of the significant advantages of CGA Gene Knockout Cell Lines is their stability and reliability. Unlike alternative methods, such as transient transfections, these knockout lines provide persistent gene disruption, which is essential for long-term experiments and detailed studies. Furthermore, their ease of use and availability make them an attractive option for labs looking to streamline their research processes.

By utilizing CGA Gene Knockout Cell Lines, researchers and clinicians can unlock valuable insights into gene function and disease mechanisms, ultimately paving the way for innovative therapeutic approaches. Our company boasts extensive expertise in cellular biology and gene editing technologies, ensuring that our products meet rigorous scientific standards while catering to the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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