Home / CFAP53 Knockout Cell Lines

CFAP53 Knockout Cell Lines

Gene: CFAP53

Official Full Name: cilia and flagella associated protein 53provided by HGNC

Gene Summary: This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning. [provided by RefSeq, Aug 2015]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28110 CFAP53 Knockout cell line (HCT 116) Human CFAP53 1:2~1:4 Negative Online Inquiry
KO28111 CFAP53 Knockout cell line (HEK293) Human CFAP53 1:3~1:6 Negative Online Inquiry

Background

CFAP53 Gene Knockout Cell Lines are precisely engineered cellular models designed to study the function of the CFAP53 gene, which is implicated in cilia formation and function. By utilizing the CRISPR/Cas9 gene-editing technology, these cell lines allow researchers to create targeted knockouts, facilitating the investigation of the gene’s specific contributions to cellular processes and signaling pathways.

The primary function of CFAP53 Gene Knockout Cell Lines lies in their ability to mimic genetic disorders related to cilia dysfunction. These cell lines enable scientists to explore the mechanisms underlying ciliopathies, diseases caused by abnormalities in cilia structure and function. By knocking out the CFAP53 gene, researchers can observe resultant phenotypic changes, analyze alterations in cellular behavior, and dissect the molecular pathways affected by the loss of this gene.

The scientific importance of these cell lines is underscored by their wide application in various research settings, including developmental biology, molecular genetics, and drug discovery. They provide an essential tool for elucidating the role of CFAP53 in human health, potentially leading to novel therapeutic strategies for cilia-related diseases.

Compared to traditional methods using non-specific inhibitors or overexpression systems, CFAP53 Gene Knockout Cell Lines offer unparalleled specificity and control, ensuring that any observed effects directly correlate with the loss of the CFAP53 gene. Their unique selling points include reproducibility, reliability, and ease of use in various laboratory environments.

For researchers and clinicians focused on novel insights into genetic diseases or drug responses, these cell lines present a compelling value proposition. They not only facilitate impactful discoveries but also enable the development of targeted therapeutics tailored to genetic profiles.

With a robust dedication to advancing biological research, our company specializes in the creation of high-quality gene knockout models that empower scientists worldwide. We are committed to providing resources that enhance understanding and drive innovation in the field of genetics.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.