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CFAP36 Knockout Cell Lines

Gene: CFAP36

Official Full Name: cilia and flagella associated protein 36provided by HGNC

Gene Summary: Located in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30885 CFAP36 Knockout cell line (HeLa) Human CFAP36 1:3~1:6 Negative Online Inquiry
KO30886 CFAP36 Knockout cell line (HCT 116) Human CFAP36 1:2~1:4 Negative Online Inquiry
KO30887 CFAP36 Knockout cell line (HEK293) Human CFAP36 1:3~1:6 Negative Online Inquiry
KO30888 CFAP36 Knockout cell line (A549) Human CFAP36 1:3~1:4 Negative Online Inquiry

Background

CFAP36 Gene Knockout Cell Lines are genetically engineered cell lines in which the CFAP36 gene has been strategically inactivated or "knocked out." This innovative approach to functional genomics provides a powerful tool for researchers aiming to explore the role of CFAP36 in cellular processes. CFAP36, a gene implicated in ciliary function and associated with various human diseases, encodes a protein that is crucial for the formation and maintenance of cilia. Through advanced CRISPR-Cas9 technology, these knockout cell lines allow for detailed study of CFAP36's biological functions and its contributions to pathophysiological conditions such as ciliopathies.

The key mechanism of these cell lines lies in their ability to facilitate the examination of gene function by eliminating CFAP36 expression, thereby enabling researchers to observe phenotypic changes and downstream effects on cellular signaling pathways, motility, and differentiation. This capability is invaluable for investigating the molecular underpinnings of ciliary dysfunction and related disorders, making this product particularly important in the advancing fields of regenerative medicine and targeted gene therapy.

Compared to traditional methods of gene manipulation, CFAP36 Gene Knockout Cell Lines offer unique advantages, including high specificity, efficiency, and the ability to generate stable cell lines that can be utilized in long-term studies. Their precision in gene editing enhances reproducibility in experimental outcomes, which is critical for the validation of findings in both basic research and clinical applications.

For researchers and clinicians, the CFAP36 Gene Knockout Cell Lines represent a vital resource in studying gene function, developing therapeutic strategies, and understanding disease mechanisms. Given their potential to accelerate discovery and innovation in disease modeling, these cell lines are an essential addition to any laboratory focused on ciliary research or genetics.

Our company prides itself on extensive expertise in the production of advanced cellular models, leveraging cutting-edge genomic technologies to provide high-quality biological products that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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