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CFAP300 Knockout Cell Lines

Gene: CFAP300

Official Full Name: cilia and flagella associated protein 300provided by HGNC

Gene Summary: Predicted to be located in cytoplasm and motile cilium. Implicated in primary ciliary dyskinesia 38. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24338 CFAP300 Knockout cell line (HeLa) Human CFAP300 1:3~1:6 Negative Online Inquiry
KO24339 CFAP300 Knockout cell line (HEK293) Human CFAP300 1:3~1:6 Negative Online Inquiry
KO24340 CFAP300 Knockout cell line (A549) Human CFAP300 1:3~1:4 Negative Online Inquiry

Background

CFAP300 Gene Knockout Cell Lines are a specifically engineered set of mammalian cell lines in which the CFAP300 gene has been disrupted, allowing researchers to study the gene’s function and related biological pathways. These knockout cell lines serve as crucial tools for investigating the role of CFAP300 in cell motility, ciliogenesis, and cellular signaling—key processes implicated in various human diseases, including cancer and ciliopathies.

The primary function of CFAP300 involves its role as a structural component of cilia, which are hair-like projections on the surface of cells that facilitate motility and sensory functions. By employing CRISPR-Cas9 gene editing technology, the CFAP300 Gene Knockout Cell Lines facilitate precise genomic alterations, enabling researchers to elucidate the downstream effects of CFAP300 loss in cellular contexts. This may include changes in cell adhesion, migration patterns, and responses to extracellular signals, thus providing a platform for exploring therapeutic targets and drug responses.

Scientifically, these cell lines are invaluable in both research and clinical settings. They not only provide insight into fundamental biological processes but also serve as an excellent model for drug screening and development—particularly for therapies targeting diseases associated with dysfunctional cilia. Moreover, the use of CFAP300 knockout models can help in understanding the genetic basis of various pathological conditions, paving the way for personalized medicine approaches.

What sets our CFAP300 Gene Knockout Cell Lines apart from alternatives on the market is the rigorous validation and characterization they undergo, ensuring reliability and reproducibility of results in experiments. These cell lines are derived from well-defined and widely used parent cell lines, which enhances their application in comparative studies and real-world experimental settings.

For researchers and clinicians aiming to deepen their understanding of ciliary function and related disorders, our CFAP300 Gene Knockout Cell Lines represent a significant resource. They provide a robust foundation for innovative research and facilitate breakthroughs in our understanding of complex biological systems. Through our commitment to high-quality biological products and an expert team dedicated to advancing scientific discovery, we are proud to offer research tools that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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