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CFAP251 Knockout Cell Lines

Gene: CFAP251

Official Full Name: cilia and flagella associated protein 251provided by HGNC

Gene Summary: This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24106 CFAP251 Knockout cell line (HCT 116) Human CFAP251 1:2~1:4 Negative Online Inquiry
KO24107 CFAP251 Knockout cell line (A549) Human CFAP251 1:3~1:4 Negative Online Inquiry

Background

CFAP251 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CFAP251 gene, which encodes a protein implicated in ciliary function and cellular signaling pathways. These knockout cell lines are invaluable tools in molecular biology, enabling researchers to explore the role of CFAP251 in various biological contexts, particularly in the study of cilia-related diseases and developmental biology.

The primary function of these cell lines is to provide insights into the phenotypic consequences of CFAP251 deletion, including alterations in cell morphology, motility, and signaling pathways associated with cell adhesion and differentiation. Through techniques such as gene expression analysis, protein profiling, and cellular assays, researchers can delineate the specific roles that CFAP251 plays in health and disease.

In clinical and research settings, CFAP251 Gene Knockout Cell Lines hold significant scientific importance, particularly for investigations into genetic disorders linked to ciliary dysfunction, such as primary ciliary dyskinesia. By understanding the mechanisms through which CFAP251 operates, scientists can uncover potential therapeutic targets and develop novel interventions to address these conditions.

Compared to traditional models that may not fully recapitulate the in vivo environment, our CFAP251 Gene Knockout Cell Lines offer a more precise and relevant system for studying gene function. They provide researchers with a clean genetic background, enhancing reproducibility and data reliability in experiments aimed at elucidating gene function and pathology.

These cell lines represent a critical advancement in biological research, equipping scientists with the necessary tools to bridge basic science and clinical applications comprehensively. Our commitment to excellence is reflected in our expertise in genetic engineering and cell line development, ensuring that our CFAP251 Gene Knockout Cell Lines meet the highest standards for quality and performance to support your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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