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CFAP144 Knockout Cell Lines

Gene: CFAP144

Official Full Name: cilia and flagella associated protein 144provided by HGNC

Gene Summary: Enables microtubule binding activity. Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18775 CFAP144 Knockout cell line (HEK293) Human CFAP144 1:3~1:6 Negative Online Inquiry
KO18776 CFAP144 Knockout cell line (A549) Human CFAP144 1:3~1:4 Negative Online Inquiry

Background

CFAP144 Gene Knockout Cell Lines are advanced research tools designed to facilitate the study of the CFAP144 gene's function and its implications in cellular processes. These cell lines are generated using state-of-the-art CRISPR/Cas9 technology, enabling precise genetic modifications to create specific knockout models, where the CFAP144 gene has been completely inactivated. This targeted approach allows researchers to investigate the biological consequences of CFAP144 deficiency, providing insights into its role in ciliary function, sperm motility, and potential links to various diseases, including infertility and ciliopathies.

The key mechanisms by which CFAP144 Gene Knockout Cell Lines operate stem from the absence of the CFAP144 protein, which is essential for the assembly and stability of cilia and flagella. By studying these knockout cell lines, researchers can elucidate the molecular pathways impacted by CFAP144 disruption and assess downstream effects on cellular signaling and motility. This specific focus on gene knockout not only enhances the understanding of the CFAP144 gene but also serves as a model for other genes with similar functions.

Scientifically, these cell lines are invaluable in both basic research and clinical settings, particularly for investigating gene function and contributing to the development of gene therapies. They present a unique platform for drug screening and the exploration of therapeutic interventions aimed at diseases associated with ciliary dysfunction.

Unlike other gene knockout products, CFAP144 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility in genetic modifications, significantly streamlining the research process. With validated performance metrics, a robust genetic background, and a wide range of applications, these cell lines provide a competitive edge in molecular and cellular biology studies.

For researchers, clinicians, and biotechnology companies focused on genetic research and therapeutic development, CFAP144 Gene Knockout Cell Lines deliver a powerful tool that enhances experimental accuracy and depth of understanding. Renowned for our commitment to quality and reliability, our company has a track record of providing cutting-edge biological products that empower scientific innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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