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CEP83 Knockout Cell Lines

Gene: CEP83

Official Full Name: centrosomal protein 83provided by HGNC

Gene Summary: The protein encoded by this gene is a centriolar protein involved in primary cilium assembly. Defects in this gene have been associated with infantile nephronophthisis and intellectual disability. [provided by RefSeq, Oct 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22967 CEP83 Knockout cell line (HeLa) Human CEP83 1:3~1:6 Negative Online Inquiry
KO22968 CEP83 Knockout cell line (HCT 116) Human CEP83 1:2~1:4 Negative Online Inquiry
KO22969 CEP83 Knockout cell line (HEK293) Human CEP83 1:3~1:6 Negative Online Inquiry
KO22970 CEP83 Knockout cell line (A549) Human CEP83 1:3~1:4 Negative Online Inquiry

Background

CEP83 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the CEP83 gene's function and its role in cellular processes. These cell lines are meticulously developed through CRISPR-Cas9 technology, allowing for precise gene editing that disrupts the expression of the CEP83 gene. This knockout enables researchers to investigate the biological mechanisms underlying critical cellular functions, particularly those related to cilia formation and primary ciliary dyskinesia.

The primary function of the CEP83 gene is to encode a protein that is integral to the assembly and maintenance of cilia, which play pivotal roles in signaling pathways, fluid movement, and sensing environmental cues in various cell types. By utilizing the CEP83 Gene Knockout Cell Lines, researchers can elucidate the molecular pathways impacted by the loss of this gene, paving the way for discoveries related to developmental biology, genetic diseases, and potential therapeutic targets.

In research and clinical settings, these cell lines hold considerable scientific importance. They serve as indispensable tools for modeling human diseases linked to ciliary dysfunction, enabling drug screening and the identification of novel biomarkers. Unlike traditional cell lines, which may retain partial gene functionality, the complete knockout of CEP83 provides a more accurate representation of the gene's absence, enhancing the reliability of experimental results.

One of the notable advantages of choosing the CEP83 Gene Knockout Cell Lines over other models is their enhanced specificity and precision in studying CEP83-related pathways. Our optimized protocols ensure high efficiency in gene editing with reproducible outcomes, saving researchers valuable time and resources. Furthermore, these cell lines are ready to usage, allowing immediate integration into existing research workflows.

Collaboration with our company not only grants access to this top-tier biological product but also to our extensive expertise in cellular engineering and gene editing techniques. We are dedicated to advancing scientific research and providing resources that empower researchers and clinicians to achieve meaningful insights into genetics and cellular behavior.

Please note that all services are for research use only. Not intended for any clinical use.

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