Gene: CEP55
Official Full Name: centrosomal protein 55provided by HGNC
Gene Summary: Enables identical protein binding activity. Involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body and centrosome. Implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00360 | CEP55 gRNA6 KO plasmid | CEP55 | $850 | |||
GP00543 | CEP55 gRNA1-gRNA2 KO plasmid | CEP55 | $850 | |||
KO18824 | CEP55 Knockout cell line (HeLa) | Human | CEP55 | 1:3~1:6 | Negative | Online Inquiry |
KO18825 | CEP55 Knockout cell line (HCT 116) | Human | CEP55 | 1:2~1:4 | Negative | Online Inquiry |
KO18826 | CEP55 Knockout cell line (HEK293) | Human | CEP55 | 1:3~1:6 | Negative | Online Inquiry |
CEP55 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the role of the CEP55 gene in cellular processes such as cytokinesis and cell division. By creating a knockout of the CEP55 gene, these cell lines enable researchers to investigate the downstream effects of its absence, allowing for a deeper understanding of its involvement in malignant cell behavior and other pathological conditions.
The key mechanism of action of the CEP55 knockout cell lines lies in their ability to provide insight into the essential biological pathways dictated by CEP55. This gene encodes a protein crucial for the completion of cytokinesis, and its absence can lead to aberrant cell division, resulting in multinucleation and ultimately, cellular dysfunction. Researchers can utilize these models to explore cellular responses to various stimuli, assess drug efficacy, and investigate the genetic basis of diseases linked to cell division errors.
Scientifically, these knockout cell lines are vital tools in both basic and translational research settings. They facilitate the discovery of novel therapeutic targets for cancer treatment, elucidate tumorigenesis pathways, and contribute to the development of precision medicine strategies for conditions tied to cell cycle dysregulation. Their applications extend to understanding developmental biology and tissue regeneration, highlighting their versatile utility in numerous research contexts.
What sets CEP55 Gene Knockout Cell Lines apart from traditional models is their specificity and ease of use. While other cell lines may exhibit off-target effects that confound results, these engineered lines provide clear insight into the particular role of the CEP55 gene, ensuring reliable experimental outcomes. Their reproducibility and consistent genetic background further enhance experimental validation for researchers.
For researchers and clinicians striving for breakthroughs in cancer biology and related fields, CEP55 Gene Knockout Cell Lines represent an invaluable resource, allowing for targeted investigations into cell division dynamics and the implications of disrupted cellular processes. Our company is dedicated to advancing scientific knowledge with a portfolio of high-quality biological products, underpinned by years of expertise in genetic engineering and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.