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CELF4 Knockout Cell Lines

Gene: CELF4

Official Full Name: CUGBP Elav-like family member 4provided by HGNC

Gene Summary: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18840 CELF4 Knockout cell line (HeLa) Human CELF4 1:3~1:6 Negative Online Inquiry

Background

CELF4 Gene Knockout Cell Lines are genetically modified cell lines designed to specifically target and eliminate the CELF4 gene, which plays a critical role in post-transcriptional regulation of gene expression. These cell lines utilize CRISPR-Cas9 technology to achieve precise gene knockout, enabling researchers to study the functional implications of CELF4 deletion on cellular processes. The CELF4 protein is implicated in diverse biological functions, including mRNA splicing, stability, and transport, making these cell lines invaluable for dissecting the pathways influenced by this gene.

The primary function of CELF4 Gene Knockout Cell Lines is to provide a robust platform for investigating the role of CELF4 in various physiological and pathological contexts, such as neurological disorders and cancer. By removing this gene, researchers can examine alterations in gene expression profiles, signaling pathways, and cellular behaviors, shedding light on underlying mechanisms of diseases where CELF4 is believed to be a contributing factor.

In scientific research and clinical settings, CELF4 Gene Knockout Cell Lines stand out due to their ability to model disease states accurately. They enable targeted investigations that can lead to new therapeutic strategies or biomarkers for conditions influenced by CELF4 dysregulation. Moreover, the application of this technology extends to fields like pharmacogenomics, where understanding the interaction of drugs with CELF4-related pathways can enhance personalized medicine approaches.

Compared to traditional gene knockout methods, CELF4 Gene Knockout Cell Lines offer significant advantages, including high efficiency, specificity, and the ability to generate stable cell lines with minimal off-target effects. This precision allows for reproducible experimental results and facilitates downstream applications such as high-throughput screening and phenotypic characterization.

This product is particularly valuable for molecular biologists, pharmacologists, and clinical researchers focused on gene regulation, cellular development, and therapeutic interventions. By utilizing our CELF4 Gene Knockout Cell Lines, researchers can accelerate their discoveries in gene function and disease mechanisms, ultimately contributing to advances in medical research and treatment.

With a robust track record in genetic engineering and an unwavering commitment to scientific innovation, our company is dedicated to providing high-quality biological products that empower researchers in their quest for knowledge and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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