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CEBPB Knockout Cell Lines

Gene: CEBPB

Official Full Name: CCAAT enhancer binding protein betaprovided by HGNC

Gene Summary: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01453 CEBPB Knockout cell line(ZR75-1) Human CEBPB Negative Online Inquiry
KO08360 CEBPB Knockout cell line (HeLa) Human CEBPB 1:3~1:6 Negative Online Inquiry
KO08361 CEBPB Knockout cell line (HCT 116) Human CEBPB 1:2~1:4 Negative Online Inquiry
KO08362 CEBPB Knockout cell line (HEK293) Human CEBPB 1:3~1:6 Negative Online Inquiry
KO08363 CEBPB Knockout cell line (A549) Human CEBPB 1:3~1:4 Negative Online Inquiry

Background

CEBPB Gene Knockout Cell Lines are meticulously developed cellular models that specifically lack the CEBPB gene, a critical transcription factor involved in a myriad of biological processes, including cellular differentiation, inflammation, and metabolism. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with a robust platform to investigate the functional roles of CEBPB in various cellular contexts.

The primary function of CEBPB is to regulate gene expression in response to environmental stimuli, playing a significant role in immune responses and glucose metabolism. The knockout of this gene enables the detailed analysis of downstream effects on cellular behavior, signaling pathways, and gene expression profiles, thus serving as a powerful tool in dissecting biological mechanisms.

In clinical and research applications, CEBPB Gene Knockout Cell Lines have profound implications, particularly in studies aimed at understanding diseases such as obesity, diabetes, and certain cancers where CEBPB activity is often dysregulated. These cell lines can serve as valuable models in drug discovery, allowing researchers to assess therapeutic targets and evaluate the efficacy of new compounds in the context of CEBPB modulation.

What sets our CEBPB Gene Knockout Cell Lines apart from alternative models is their high specificity and the efficiency of the gene knockout process, which ensures minimal off-target effects. This precision is essential for producing reliable and reproducible experimental results. Furthermore, our commitment to quality control and adherence to rigorous scientific standards guarantees that these cell lines are authenticated and validated for various experimental needs.

For researchers and clinicians focused on understanding complex cellular mechanisms or developing targeted therapies, CEBPB Gene Knockout Cell Lines represent an invaluable asset. By providing the tools to elucidate the functions of this gene, we empower the scientific community to make groundbreaking discoveries. Our company prides itself on its expertise in developing high-quality biological products, ensuring that our offerings contribute significantly to the advancement of scientific research and clinical practice.

Please note that all services are for research use only. Not intended for any clinical use.

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