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CDKL2 Knockout Cell Lines

Gene: CDKL2

Official Full Name: cyclin dependent kinase like 2provided by HGNC

Gene Summary: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33663 CDKL2 Knockout cell line (HEK293) Human CDKL2 1:3~1:6 Negative Online Inquiry
KO33664 CDKL2 Knockout cell line (A549) Human CDKL2 1:3~1:4 Negative Online Inquiry

Background

CDKL2 Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically disable the cyclin-dependent kinase-like 2 (CDKL2) gene, which is crucial in regulating cell cycle progression and differentiation. By utilizing advanced CRISPR/Cas9 technology, these cell lines enable researchers to study the biological implications of CDKL2 deficiency, allowing for detailed understanding of its role in various cellular processes.

The primary function of these knockout cell lines is to facilitate the investigation of CDKL2's involvement in tumorigenesis, neurodevelopment, and cellular signaling pathways. This is achieved by analyzing how the absence of CDKL2 affects cellular proliferation, apoptosis, and response to external stimuli. Researchers can employ these cell lines in vitro to elucidate the molecular mechanisms that are disrupted when CDKL2 is knocked out, thus providing valuable data for therapeutic strategy development.

In the realm of scientific research and clinical applications, CDKL2 knockout cell lines hold significant importance. Their utility extends to studies focused on cancer biology, neurological disorders, and drug development. As CDKL2's involvement in various disease models is becoming increasingly evident, these cell lines serve as a critical tool for preclinical evaluations of targeted therapies aimed at restoring normal cell function or inhibiting aberrant pathways.

The advantages of CDKL2 Gene Knockout Cell Lines compared to alternatives lie in their specificity and versatility. Unlike traditional methods that may produce off-target effects, CRISPR/Cas9 provides homogeneous populations with precise and reproducible gene editing. Furthermore, these knockout lines can be integrated into existing experimental frameworks, providing a seamless transition for researchers looking to expand their investigations.

For researchers and clinicians, the value of CDKL2 Gene Knockout Cell Lines is particularly pronounced. They offer a robust mechanism for exploring gene function and pathology, enabling novel discoveries that could lead to breakthroughs in treatment strategies for diverse diseases associated with CDKL2 dysregulation.

With a solid foundation in genetic engineering and a commitment to advancing scientific research, our company specializes in providing high-quality biological products tailored to the needs of the scientific community. We take pride in our ability to deliver precise and innovative tools that empower researchers to push the boundaries of knowledge and therapeutic interventions.

Please note that all services are for research use only. Not intended for any clinical use.

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