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CDK2AP2 Knockout Cell Lines

Gene: CDK2AP2

Official Full Name: cyclin dependent kinase 2 associated protein 2provided by HGNC

Gene Summary: This gene encodes a protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32059 CDK2AP2 Knockout cell line (HeLa) Human CDK2AP2 1:3~1:6 Negative Online Inquiry
KO32060 CDK2AP2 Knockout cell line (HCT 116) Human CDK2AP2 1:2~1:4 Negative Online Inquiry
KO32061 CDK2AP2 Knockout cell line (HEK293) Human CDK2AP2 1:3~1:6 Negative Online Inquiry
KO32062 CDK2AP2 Knockout cell line (A549) Human CDK2AP2 1:3~1:4 Negative Online Inquiry

Background

CDK2AP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the cyclin-dependent kinase 2 associated protein 2 (CDK2AP2) gene, a crucial regulator of the cell cycle and cellular proliferation. By creating a knockout model of this gene, researchers can study the implications of CDK2AP2 deficiency on cellular processes and signaling pathways, enabling a deeper understanding of its role in tumorigenesis and other pathophysiological conditions.

The primary function of the CDK2AP2 gene involves the modulation of cyclin-dependent kinase activity, impacting the transition from the G1 to S phase of the cell cycle. CDK2AP2 serves as a protective factor against unregulated cell division; therefore, its absence can lead to enhanced cell proliferation or altered cell fate decisions. Researchers utilize these knockout cell lines to investigate the downstream effects of CDK2AP2 depletion, including changes in apoptosis, differentiation, and metabolic pathways.

In the realm of scientific and clinical research, CDK2AP2 knockout cell lines hold significant value. They provide a robust platform for drug testing, molecular biology studies, and the exploration of cancer biology, particularly in understanding how CDK2AP2 loss may correlate with aggressive malignancies or resistance to therapy. This makes them essential tools for researchers aiming to develop targeted therapies or novel treatment strategies.

One of the key advantages of using CDK2AP2 knockout cell lines is their specificity and reproducibility in experimental design, allowing for precise control over genetic variables that can be manipulated. Compared to other general knockouts, these lines are tailored for studies focusing on cell cycle regulation and cancer progression, offering unique insights that would be difficult to obtain with less specific models.

Our product is invaluable to researchers and clinicians alike who seek to unravel the complexities of cell cycle regulation and its implications in disease. By employing our CDK2AP2 Gene Knockout Cell Lines in research, users can expect enhanced outcomes in their experiments, leading to impactful discoveries and advancements in technical applications. Our company prides itself on providing high-quality biological tools backed by rigorous scientific research, ensuring that our customers are equipped with the best resources for their innovative endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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