Gene: CDK20
Official Full Name: cyclin dependent kinase 20provided by HGNC
Gene Summary: The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29130 | CDK20 Knockout cell line (HeLa) | Human | CDK20 | 1:3~1:6 | Negative | Online Inquiry |
KO29131 | CDK20 Knockout cell line (HCT 116) | Human | CDK20 | 1:2~1:4 | Negative | Online Inquiry |
KO29132 | CDK20 Knockout cell line (HEK293) | Human | CDK20 | 1:3~1:6 | Negative | Online Inquiry |
KO29133 | CDK20 Knockout cell line (A549) | Human | CDK20 | 1:3~1:4 | Negative | Online Inquiry |
CDK20 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of Cyclin-Dependent Kinase 20 (CDK20), a regulatory enzyme involved in the cell cycle's progression and function. These cell lines have been meticulously developed using CRISPR/Cas9 technology to induce a knockout of the CDK20 gene, allowing researchers to analyze the consequent effects on cellular processes such as proliferation, differentiation, and apoptosis.
The primary function of these cell lines is to provide a transparent model for investigating the role of CDK20 in various biological pathways. By enabling the observation of alterations in signaling cascades associated with CDK20 inhibition or loss, researchers can uncover crucial insights into its contributions to diseases, particularly cancers and developmental disorders. The precision of gene knockout allows for unequivocal assessments of CDK20's functions, leading to a deeper understanding of its potential as a therapeutic target.
In terms of scientific importance, these knockout cell lines are invaluable in both basic and applied research contexts. They can be leveraged in high-throughput screening for drug discovery, particularly in compounds that may target CDK20-mediated pathways. Furthermore, their applications extend to the fields of cell biology, genetics, and oncology, providing a versatile platform for dissecting tumorigenic mechanisms and validating potential therapeutic interventions.
What sets our CDK20 Gene Knockout Cell Lines apart from alternatives on the market is the robust validation of knockout efficiency and phenotype changes, ensuring that users receive cell lines that exhibit consistent and reproducible outcomes. Additionally, our lines are supplied with comprehensive characterization data, enhancing their reliability for critical research needs.
For researchers and clinicians focused on gene function and regulatory mechanisms, the utility of our CDK20 knockout models is clear. They represent a powerful tool for elucidating the roles of cyclin-dependent kinases in health and disease, potentially leading to novel avenues for intervention in cancer and beyond. With years of expertise in developing cutting-edge biological products, our company is committed to advancing scientific discovery through high-quality, reliable research tools that empower our users.
Please note that all services are for research use only. Not intended for any clinical use.
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