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CDH15 Knockout Cell Lines

Gene: CDH15

Official Full Name: cadherin 15provided by HGNC

Gene Summary: This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38613 CDH15 Knockout cell line (HCT 116) Human CDH15 1:2~1:4 Negative Online Inquiry

Background

CDH15 Gene Knockout Cell Lines represent a cutting-edge tool for exploring the functions of cadherin-related proteins, specifically the cadherin-15 gene, within cellular processes. This product consists of genetically engineered cell lines that have had the CDH15 gene precisely disrupted using CRISPR/Cas9 technology, enabling researchers to dissect the molecular mechanisms underlying cell adhesion, neurodevelopment, and associated pathologies.

The primary function of these knockout cell lines is to facilitate in-depth studies on how the loss of CDH15 impacts cell behavior, morphology, and intracellular signaling pathways. The mechanism of action involves the ablation of the gene product, which is critical for maintaining cellular integrity and facilitating intercellular interactions. This provides an invaluable model for investigating CDH15's role in developmental biology, cancer metastasis, and neurological disorders, where its dysregulation may contribute to disease progression.

From a scientific perspective, the importance of CDH15 Gene Knockout Cell Lines cannot be overstated. They serve as critical models for elucidating the complexities of cell adhesion, enabling researchers to make significant advances in understanding cellular dynamics in health and disease. Additionally, they provide valuable platforms for drug discovery and therapeutic development by allowing for high-throughput screening conditions that mimic pathological states.

One of the distinct advantages of our CDH15 Gene Knockout Cell Lines is their robust validation, ensuring specificity and reproducibility across experimental conditions. Compared to alternative models, these cell lines provide a more accurate reflection of in vivo conditions, thereby increasing the relevance of experimental findings. Furthermore, when paired with our technical support and consultation services, researchers can maximize their experimental designs, ensuring optimal outcomes.

Investing in CDH15 Gene Knockout Cell Lines is an essential step for researchers and clinicians aiming to push the boundaries of genetic research and therapeutic innovation. Our commitment to excellence in genetic engineering and cellular models positions us as a leading provider in this field, consistently delivering high-quality products that empower scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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