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CDC37L1 Knockout Cell Lines

Gene: CDC37L1

Official Full Name: cell division cycle 37 like 1, HSP90 cochaperoneprovided by HGNC

Gene Summary: CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20247 CDC37L1 Knockout cell line (HeLa) Human CDC37L1 1:3~1:6 Negative Online Inquiry
KO20248 CDC37L1 Knockout cell line (HCT 116) Human CDC37L1 1:2~1:4 Negative Online Inquiry
KO20249 CDC37L1 Knockout cell line (HEK293) Human CDC37L1 1:3~1:6 Negative Online Inquiry
KO20250 CDC37L1 Knockout cell line (A549) Human CDC37L1 1:3~1:4 Negative Online Inquiry

Background

CDC37L1 Gene Knockout Cell Lines are a specialized tool designed for in-depth studies of gene function and the molecular pathways involved in cellular processes. These cell lines are engineered to have a targeted disruption of the CDC37L1 gene, a critical component implicated in the regulation of cellular chaperone proteins and involved in various cellular stress responses. By creating a knockout model, researchers can elucidate the role of CDC37L1 in biological systems by comparing the knockout cells with wild-type cells, thus allowing for a clearer understanding of its contributions to cellular growth, differentiation, and response to external stimuli.

The key mechanism of action in these cell lines lies in the absence of the CDC37L1 protein, which serves to affect the stability and activity of various client proteins involved in cell signaling pathways. This unique approach allows researchers to investigate the downstream effects of CDC37L1 deficiency, making it an indispensable resource for studies focused on cancer biology, metabolic disorders, and stress response mechanisms. The ability to manipulate gene expression in a controlled environment enhances the capability to draw connections between genetic alterations and phenotypic outcomes.

In scientific research and clinical settings, these knockout cell lines serve as a robust model for drug discovery, therapeutic testing, and biomarker identification. They provide a platform for screening potential therapeutic compounds and investigating their mechanisms of action in the context of CDC37L1 deficiency. Compared to alternative models, such as transient transfection systems or conventional whole-animal models, CDC37L1 Gene Knockout Cell Lines offer a more precise and manageable approach, facilitating high-throughput experiments with reproducible results.

Moreover, the stability and authenticity of these cell lines ensure that researchers can achieve reliable data, making them a valuable asset in laboratories focused on genetic research or disease modeling.

Our company is committed to providing high-quality biological tools and resources, and our expertise in developing specialized cell lines ensures that researchers and clinicians have access to the best solutions for their experimental needs. The CDC37L1 Gene Knockout Cell Lines exemplify our dedication to facilitating advancements in scientific research and contributing to the understanding of complex biological processes.

Please note that all services are for research use only. Not intended for any clinical use.

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