Gene: CD79A
Official Full Name: CD79a moleculeprovided by HGNC
Gene Summary: The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38641 | CD79A Knockout cell line (HEK293) | Human | CD79A | 1:3~1:6 | Negative | Online Inquiry |
CD79A Gene Knockout Cell Lines represent a pioneering advance in the study of B-cell development and function, specifically targeting the CD79A gene, which encodes an essential component of the B-cell receptor (BCR) complex. These genetically modified cell lines are created through advanced CRISPR/Cas9 gene editing techniques, effectively disabling the CD79A gene to facilitate investigation into the physiological and pathological roles of B cells.
The primary function of the CD79A knockout cell lines is to elucidate the role of BCR signaling in various immunological processes, including the activation of B lymphocytes, antibody production, and the underlying mechanisms of autoimmunity. By removing the CD79A gene, researchers can observe how B cells behave in the absence of functional BCRs, shedding light on compensatory pathways that may be involved in immune responses or disease states.
The scientific importance of these cell lines is underscored by their applications in both fundamental research and clinical settings. They serve as valuable models for studying B-cell neoplasms, autoimmune disorders, and the impact of monoclonal antibody therapies. Additionally, they provide a platform for testing new treatments aimed at modulating B-cell activity.
Compared to traditional cell lines, CD79A knockout cell lines offer unique advantages, such as enhanced specificity and accuracy in simulating disease conditions, which are critical for drug development and therapeutic interventions. This precision enables researchers to generate more reliable data, ultimately contributing to advancements in immunology and oncology.
For researchers and clinicians, the value of CD79A Gene Knockout Cell Lines lies in their ability to provide insights that could lead to breakthroughs in understanding immune regulation and disease pathology. The nuanced data derived from these models can inform both basic research and therapeutic strategies, making them indispensable tools in the laboratory.
Our company specializes in high-quality biological products, equipped with the expertise to support researchers in their quest for scientific discovery. With a focus on precision gene editing technologies, we are committed to providing innovative solutions that advance research in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.