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CCSAP Knockout Cell Lines

Gene: CCSAP

Official Full Name: centriole, cilia and spindle associated proteinprovided by HGNC

Gene Summary: Enables microtubule binding activity. Involved in mitotic spindle microtubule depolymerization and regulation of mitotic spindle assembly. Located in axon; ciliary transition zone; and cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27248 CCSAP Knockout cell line (HeLa) Human CCSAP 1:3~1:6 Negative Online Inquiry
KO27249 CCSAP Knockout cell line (HCT 116) Human CCSAP 1:2~1:4 Negative Online Inquiry
KO27250 CCSAP Knockout cell line (HEK293) Human CCSAP 1:3~1:6 Negative Online Inquiry
KO27251 CCSAP Knockout cell line (A549) Human CCSAP 1:3~1:4 Negative Online Inquiry

Background

CCSAP Gene Knockout Cell Lines are specialized cell models engineered for the precise disruption of the CCSAP gene, an important component in various cellular pathways and disease processes. These knockout cell lines are created through advanced CRISPR-Cas9 technology, ensuring high specificity and efficiency in targeting the CCSAP gene. By removing the expression of CCSAP, researchers can elucidate its function, study gene interactions, and assess downstream effects in various biological contexts.

The primary function of these cell lines is to facilitate the exploration of CCSAP’s role in cellular mechanisms, disease modeling, and drug response. The knockout mechanism interrupts the gene's normal activity, allowing for comparative studies against wild-type cells. Researchers can investigate alterations in cell proliferation, differentiation, and apoptosis, enabling valuable insights into the gene's contribution to pathophysiological processes, such as cancer development and metabolic disorders.

In terms of scientific significance, CCSAP Gene Knockout Cell Lines serve as invaluable tools in both basic and translational research. They provide a platform for gene function analysis, potential therapeutic target identification, and the validation of pharmacological agents aimed at modulating CCSAP-associated pathways. Moreover, their application extends to the assessment of cellular responses to various stressors, contributing to a more comprehensive understanding of cellular resilience and vulnerability.

Unlike alternative models that require the use of gene overexpression or RNA interference strategies, CCSAP Gene Knockout Cell Lines offer a more definitive and stable means to assess gene loss-of-function effects. This direct approach reduces off-target effects and variability, resulting in more interpretable data and reproducible results.

For researchers and clinicians, the availability of CCSAP knockout lines equips them with a robust tool for advancing their studies. This not only supports preclinical development of targeted therapies but also enhances understanding of gene function in critical biological processes. Our company is dedicated to excellence in providing high-quality biological products, ensuring that researchers have access to reliable and precise tools that drive innovation and discovery in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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