Gene: CCNJ
Official Full Name: cyclin Jprovided by HGNC
Gene Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21592 | CCNJ Knockout cell line (HeLa) | Human | CCNJ | 1:3~1:6 | Negative | Online Inquiry |
KO21593 | CCNJ Knockout cell line (HCT 116) | Human | CCNJ | 1:2~1:4 | Negative | Online Inquiry |
KO21594 | CCNJ Knockout cell line (HEK293) | Human | CCNJ | 1:3~1:6 | Negative | Online Inquiry |
KO21595 | CCNJ Knockout cell line (A549) | Human | CCNJ | 1:3~1:4 | Negative | Online Inquiry |
CCNJ Gene Knockout Cell Lines are advanced cellular models designed for studying the functional consequences of CCNJ gene deletion in various biological processes. By employing state-of-the-art CRISPR-Cas9 gene editing technology, these cell lines effectively disrupt the expression of the CCNJ gene, which is implicated in critical cellular functions such as cell cycle regulation, differentiation, and proliferation.
The primary mechanism behind the utility of CCNJ Gene Knockout Cell Lines lies in their ability to provide a controlled environment in which researchers can observe the phenotypic changes resulting from the absence of the CCNJ gene. This allows for in-depth investigations into the role of CCNJ in pathophysiological conditions, including cancer, metabolic disorders, and developmental abnormalities. The precise knockout of CCNJ facilitates the study of downstream pathways and cellular responses, making these cell lines invaluable for elucidating the gene's function in both in vitro and in vivo contexts.
In the realm of scientific research and clinical applications, CCNJ Gene Knockout Cell Lines serve as powerful tools for drug discovery, biomarker identification, and the development of novel therapeutic strategies. Their capacity to mimic disease states enables researchers to screen compounds effectively, evaluate therapeutic efficacy, and understand drug resistance mechanisms.
Compared to alternative models, such as overexpression systems or RNA interference approaches, CCNJ Gene Knockout Cell Lines offer unparalleled specificity in gene disruption, presenting a more authentic representation of gene loss in biological systems. These cell lines eliminate ambiguities associated with off-target effects commonly encountered in other genetic manipulations.
For researchers and clinicians targeting gene function and therapeutic development in a range of diseases, the value of CCNJ Gene Knockout Cell Lines cannot be overstated. They not only accelerate discovery but also enhance the reliability of experimental outcomes. Our company, with its commitment to cutting-edge genetic engineering and comprehensive support, proudly offers these innovative cell lines to empower advancements in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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