Gene: CCDC90B
Official Full Name: coiled-coil domain containing 90Bprovided by HGNC
Gene Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18980 | CCDC90B Knockout cell line (HeLa) | Human | CCDC90B | 1:3~1:6 | Negative | Online Inquiry |
KO18981 | CCDC90B Knockout cell line (HCT 116) | Human | CCDC90B | 1:2~1:4 | Negative | Online Inquiry |
KO18982 | CCDC90B Knockout cell line (HEK293) | Human | CCDC90B | 1:3~1:6 | Negative | Online Inquiry |
KO18983 | CCDC90B Knockout cell line (A549) | Human | CCDC90B | 1:3~1:4 | Negative | Online Inquiry |
CCDC90B Gene Knockout Cell Lines are specifically engineered cellular models that enable precise genetic manipulation to study the function of the CCDC90B gene. This gene plays a vital role in cellular processes such as vesicle trafficking, cytoskeletal organization, and signaling pathways. The generation of knockout cell lines involves advanced CRISPR-Cas9 technology, allowing for the complete disruption of the gene, thereby allowing researchers to observe the phenotypic and molecular consequences of CCDC90B loss.
The key functions of these knockout cell lines lie in their ability to provide insights into the biological roles of CCDC90B. By studying these cell lines, researchers can elucidate the mechanisms by which CCDC90B contributes to normal cellular physiology and its potential implications in various diseases, especially in cancer biology, where aberrant expression of CCDC90B has been implicated. This makes the cell lines invaluable tools for both basic and translational research, offering potential pathways for therapeutic interventions.
One distinct advantage of using CCDC90B Gene Knockout Cell Lines is the specificity and efficiency of the CRISPR technology used in their creation. This results in a clean genetic background devoid of off-target effects, compared to older gene knockdown methods like RNA interference (RNAi), which may produce inconsistent results due to varying levels of target suppression. The precisely engineered knockout facilitates robust reproducibility in experiments, making these models superior for rigorous scientific investigation.
For researchers and clinicians, the ability to explore the consequences of gene deletion at both cellular and organismal levels is a compelling reason to incorporate CCDC90B Gene Knockout Cell Lines into their work. Whether studying fundamental biological processes or developing new therapeutic strategies, these cell lines provide a robust platform for advancing the understanding of gene function in health and disease.
Our company prides itself on its expertise in genetic engineering and cell line development, providing high-quality biological products that empower researchers to push the boundaries of scientific exploration. We are committed to delivering innovative solutions that support the discovery and enhancement of therapeutic approaches in clinical settings.
Please note that all services are for research use only. Not intended for any clinical use.
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