Gene: CCDC77
Official Full Name: coiled-coil domain containing 77provided by HGNC
Gene Summary: Located in centrosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24932 | CCDC77 Knockout cell line (HeLa) | Human | CCDC77 | 1:3~1:6 | Negative | Online Inquiry |
KO24933 | CCDC77 Knockout cell line (HCT 116) | Human | CCDC77 | 1:2~1:4 | Negative | Online Inquiry |
KO24934 | CCDC77 Knockout cell line (HEK293) | Human | CCDC77 | 1:3~1:6 | Negative | Online Inquiry |
KO24935 | CCDC77 Knockout cell line (A549) | Human | CCDC77 | 1:3~1:4 | Negative | Online Inquiry |
CCDC77 Gene Knockout Cell Lines are engineered cellular models that facilitate the study of the CCDC77 gene's function through targeted gene disruption. Utilizing CRISPR-Cas9 technology, these knockout cell lines are designed to create precise gene mutations, allowing researchers to investigate the biological roles played by the CCDC77 protein in various cellular processes. This approach enables an in-depth exploration of gene function, cellular signaling pathways, and the molecular mechanisms underlying various diseases, particularly those related to cell proliferation and differentiation.
Key functions of the CCDC77 knockout lines stem from their ability to elucidate gene expression patterns and protein interactions that are otherwise difficult to assess in intact organisms. By creating a cellular environment lacking functional CCDC77, researchers can observe compensatory mechanisms, altered phenotypes, and molecular pathways that could be obscured in wild-type cells. As such, these cell lines serve as valuable tools in drug discovery and development, toxicity screening, and the validation of new therapeutic targets.
The scientific importance of CCDC77 Gene Knockout Cell Lines is underscored by their wide applicability in academia and biotechnology sectors. They enable researchers to conduct functional genomics studies and explore how changes in gene expression correlate with disease states, providing insights into potential biomarkers for various conditions.
Compared to traditional gene silencing techniques, such as RNA interference, the immediate impact of knockout models offers significant advantages. The CRISPR-Cas9 mechanism provides a more stable and long-lasting alteration, facilitating the examination of downstream effects without the transient effects of siRNA techniques. This leads to more reliable data and reproducibility in experimental outcomes.
For researchers and clinicians focused on genetic and molecular research, CCDC77 Gene Knockout Cell Lines represent a pioneering step forward in accurately exploring gene functions and their implications in health and disease. The availability of these specialized cell lines from our company—renowned for its commitment to advancing biological research—ensures the highest quality and reliability, empowering you to drive your innovations forward with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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