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CCDC51 Knockout Cell Lines

Gene: CCDC51

Official Full Name: coiled-coil domain containing 51provided by HGNC

Gene Summary: Enables mitochondrial ATP-gated potassium channel activity. Involved in cell volume homeostasis and mitochondrial potassium ion transmembrane transport. Located in mitochondrial inner membrane. Part of mitochondrial ATP-gated potassium channel complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19018 CCDC51 Knockout cell line (HeLa) Human CCDC51 1:3~1:6 Negative Online Inquiry
KO19019 CCDC51 Knockout cell line (HCT 116) Human CCDC51 1:2~1:4 Negative Online Inquiry
KO19020 CCDC51 Knockout cell line (HEK293) Human CCDC51 1:3~1:6 Negative Online Inquiry
KO19021 CCDC51 Knockout cell line (A549) Human CCDC51 1:3~1:4 Negative Online Inquiry

Background

CCDC51 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CCDC51 gene, which plays a crucial role in various cellular processes such as ciliary function, cellular signaling, and intracellular transport mechanisms. These knockout cell lines provide researchers with a powerful tool to study the biological functions of the CCDC51 gene, its implications in disease mechanisms, and potential therapeutic targets.

The key functionality of CCDC51 Gene Knockout Cell Lines lies in their ability to dissect the genetic pathways and cellular responses modulated by CCDC51. By observing phenotypic differences, researchers can illuminate the gene’s role in ciliary assembly and maintenance, as well as in the etiology of ciliopathies—a group of disorders arising from dysfunction in cilia. The mechanism of action involves the absence of CCDC51 leading to altered protein interactions and disrupted signaling pathways, which are essential for cellular homeostasis.

Scientifically, these knockout cell lines hold significant importance in research settings focused on genetic disorders, developmental biology, and cancer research. Their application enables precise modeling of human diseases, which can accelerate drug discovery and therapeutic development. Furthermore, these cell lines facilitate functional assays that can validate the impact of CCDC51 on various cellular behaviors, thus enhancing the understanding of its biological roles.

One unique selling point of CCDC51 Gene Knockout Cell Lines is the specificity of the knockout design, which ensures that any observed effects are directly attributable to the CCDC51 gene's absence, rather than off-target effects common with alternative approaches. Compared to conventional cell lines, these knockout models offer clarity and precision, empowering researchers to achieve robust and reproducible results.

For researchers and clinicians, the value of CCDC51 Gene Knockout Cell Lines lies in their ability to provide a clearer understanding of the genetic underpinnings of disease, thereby facilitating the development of targeted therapies. The insights gained from studies using these models could lead to breakthroughs in the treatment of conditions linked to ciliary dysfunction.

With a commitment to excellence in genetic engineering and cell culture technologies, our company delivers high-quality, rigorously validated biological products such as the CCDC51 Gene Knockout Cell Lines. Our expertise ensures that you have access to reliable tools necessary for advancing your research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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