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CCDC34 Knockout Cell Lines

Gene: CCDC34

Official Full Name: coiled-coil domain containing 34provided by HGNC

Gene Summary: Involved in spermatogenesis. Located in sperm midpiece. Implicated in spermatogenic failure 76. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23558 CCDC34 Knockout cell line (HeLa) Human CCDC34 1:3~1:6 Negative Online Inquiry
KO23559 CCDC34 Knockout cell line (HCT 116) Human CCDC34 1:2~1:4 Negative Online Inquiry
KO23560 CCDC34 Knockout cell line (HEK293) Human CCDC34 1:3~1:6 Negative Online Inquiry
KO23561 CCDC34 Knockout cell line (A549) Human CCDC34 1:3~1:4 Negative Online Inquiry

Background

CCDC34 Gene Knockout Cell Lines are specifically engineered cell lines where the CCDC34 gene has been disrupted through advanced CRISPR-Cas9 technology. These cell lines serve as robust models for studying the function of CCDC34 in various biological processes, including cell cycle regulation, signal transduction, and protein interactions. By providing a platform to observe the effects of gene loss, researchers can elucidate the role of CCDC34 in cellular mechanisms and its implications in disease contexts.

The primary function of these knockout cell lines is to facilitate investigations into the phenotypic consequences of CCDC34 gene deletion. When employed in functional assays, these cells allow researchers to monitor changes in cellular behavior, such as proliferation, apoptosis, and motility, providing valuable insights into the gene’s role in maintaining cellular homeostasis. Mechanistically, the absence of CCDC34 can reveal compensatory pathways activated in its absence, further deepening our understanding of its cellular functions.

The scientific importance of CCDC34 Gene Knockout Cell Lines is evident in both research and clinical settings. In cancer research, for example, they can be utilized to identify potential therapeutic targets and biomarkers associated with specific malignancies wherein CCDC34 is implicated. Additionally, these cell lines can be indispensable tools for drug screening and validation, enhancing the efficiency of the drug development pipeline.

Compared to traditional knockdown strategies, CCDC34 Gene Knockout Cell Lines offer several advantages: a complete loss of gene function, reduced off-target effects, and stability for prolonged studies. These features make them preferable for elucidative research compared to transient transfection approaches or RNA interference techniques, which may yield inconsistent results and require ongoing validation.

For researchers and clinicians, the value of CCDC34 Gene Knockout Cell Lines lies in their capacity to provide evidence-based insights critical for advancing scientific knowledge and therapeutic strategies. By leveraging these models, users can accelerate discovery in their fields and contribute to groundbreaking advancements in healthcare.

Our company prides itself on delivering high-quality, validated biological products that enhance research efficiency and innovation. By employing state-of-the-art techniques and rigorous quality controls, we ensure that our CCDC34 Gene Knockout Cell Lines are a reliable resource for your investigative needs.

Please note that all services are for research use only. Not intended for any clinical use.

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