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CCDC146 Knockout Cell Lines

Gene: CCDC146

Official Full Name: coiled-coil domain containing 146provided by HGNC

Gene Summary: Involved in spermatid development. Located in several cellular components, including microtubule organizing center; midbody; and sperm flagellum. Implicated in spermatogenic failure 94. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18956 CCDC146 Knockout cell line (HCT 116) Human CCDC146 1:2~1:4 Negative Online Inquiry
KO18957 CCDC146 Knockout cell line (A549) Human CCDC146 1:3~1:4 Negative Online Inquiry

Background

CCDC146 Gene Knockout Cell Lines are specialized cell models engineered to facilitate the study of the CCDC146 gene, which is implicated in various cellular processes, including cytoskeletal dynamics and cellular signaling. This product enables researchers to explore the functional implications of CCDC146 deficiency, providing a unique opportunity to understand its role in health and disease.

The key function of CCDC146 Gene Knockout Cell Lines lies in their ability to provide a controlled environment where the absence of the CCDC146 gene can be studied at both molecular and phenotypic levels. Utilizing CRISPR/Cas9 gene-editing technology, these cell lines are created to specifically disable the gene, allowing researchers to observe resultant changes in cellular behaviors such as proliferation, differentiation, and response to various stimuli. This robust mechanism of action ensures accurate representation of the consequences of gene knockout, making it an invaluable tool for functional genomics.

The scientific importance of these cell lines cannot be overstated; they are essential for elucidating the roles of CCDC146 in cancer biology, developmental disorders, and other pathophysiological conditions. In research settings, these models can accelerate drug discovery processes by identifying potential therapeutic targets or assessing the impact of small molecules on CCDC146-deficient cells. Clinically, understanding the genetic underpinnings related to CCDC146 can guide personalized medicine approaches, enhancing treatment efficacy.

Compared to traditional gene-editing methods, CCDC146 Gene Knockout Cell Lines offer a more efficient and seamless approach to gene inactivation, reducing variability and increasing reproducibility of results. The high fidelity of the gene knockout enhances confidence in experimental outcomes, making these cell lines superior to standard parental cell lines.

For researchers and clinicians, the value of CCDC146 Gene Knockout Cell Lines lies in their ability to deepen our understanding of disease mechanisms, ultimately contributing to the advancement of therapeutic interventions. By choosing our product, users tap into a rich resource of genetic insights leading to innovative discoveries.

Our company prides itself on being at the forefront of biological research tools, offering cutting-edge products backed by in-depth expertise in genetic engineering and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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